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Terpinen-4-ol

Name: Terpinen-4-ol
Brand: TargetMol
SKU: TN2264
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN2264Cas No. 562-74-3

Alias Terpinine-4-ol, 4-Carvomenthenol

Terpinen-4-ol (4-Carvomenthenol) is a natural compound derived from Pimpinella yunnanensis.

Terpinen-4-ol

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Catalog No. TN2264Alias Terpinine-4-ol, 4-CarvomenthenolCas No. 562-74-3

Terpinen-4-ol (4-Carvomenthenol) is a natural compound derived from Pimpinella yunnanensis.

Pack Size	Price	USA Warehouse	Global Warehouse
200 mg	$30	In Stock	In Stock
500 mg	$52	-	In Stock
1 g	$77	-	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:≥95%

Appearance:Liquid

Color:Transparent

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COA HNMR

Product Introduction

Terpinen-4-ol AI Summary

Terpinen-4-ol demonstrates a wide range of biological activities. As an antioxidant, it exhibits DPPH radical scavenging activity with an EC50 value of 53700.0 µg/mL. The compound also shows antimicrobial effectiveness against numerous microorganisms, including Bacillus subtilis, Brevibacterium ammoniagenes, and Staphylococcus aureus, with MIC values typically above 800.0 µg/mL; however, it is notably more effective against Pityrosporum ovale with a MIC of 100.0 µg/mL. Against specific pathogens, it demonstrates significant activity, such as 90.5% and 112.7% growth inhibition of Staphylococcus aureus MN8 at 6.50 mM and 0.65 mM, respectively, and notable inhibition of toxin TSST-1 production. In terms of acaricidal properties, Terpinen-4-ol shows 100% activity against Psoroptes cuniculi at dilutions ranging from 1% to 0.125% in direct contact assays after 48 hours, and similarly high activity in inhalation assays at 6 µL after 24 hours. The compound also exhibits nematicidal activity against Meloidogyne incognita J2 larvae, with EC50 values decreasing from 392.0 µg/mL at 24 hours to 168.0 µg/mL at 96 hours. Additionally, the compound demonstrates potent antifungal activity, including 100.0% growth inhibition of Aspergillus flavus at 60 µL and 20 µL concentrations, and effective inhibition of Corticium sp. and Pythium sp. at 1000 ppm with 98.3% growth inhibition. It shows moderate to high antifungal activity against Histoplasma capsulatum and Coccidioides posadasii, with MIC values ranging from 10.0 µg/mL to 250.0 µg/mL across different phases. Terpinen-4-ol also possesses substantial insecticidal activity against Leptinotarsa decemlineata, causing 100% mortality in certain life stages and conditions. Moreover, it displays bioactivity in assays measuring human recombinant UGT1A4 activity and reveals myorelaxant effects on rabbit duodenum (IC50 of 170000.0 nM) and cytotoxicity against human HL60 cells (IC50 of 30000.0 nM)..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Terpinen-4-ol (4-Carvomenthenol) is a natural compound derived from Pimpinella yunnanensis.
Synonyms	Terpinine-4-ol, 4-Carvomenthenol

Chemical Properties

Molecular Weight	154.25
Formula	C₁₀H₁₈O
Cas No.	562-74-3
Smiles	C(C)(C)C1(O)CCC(C)=CC1
Relative Density.	0.931g/mLat 25

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 27.5 mg/mL (178.28 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (12.97 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.4830 mL	32.4149 mL	64.8298 mL	324.1491 mL
5 mM	1.2966 mL	6.4830 mL	12.9660 mL	64.8298 mL
10 mM	0.6483 mL	3.2415 mL	6.4830 mL	32.4149 mL
20 mM	0.3241 mL	1.6207 mL	3.2415 mL	16.2075 mL
50 mM	0.1297 mL	0.6483 mL	1.2966 mL	6.4830 mL
100 mM	0.0648 mL	0.3241 mL	0.6483 mL	3.2415 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc