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CD39 Protein, Cynomolgus, Rhesus, Recombinant (His)
(Synonyms: ectonucleoside triphosphate diphosphohydrolase 1) Copy Product InfoSynonyms: ectonucleoside triphosphate diphosphohydrolase 1
Catalog No. TMPY-05151 Copy Product Info
Purity: 95.9%
CD39 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 51.8 kDa and the accession number is XP_015311944.1&XP_015003298.1.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $63 | - | In Stock | |
| 10 µg | $100 | - | In Stock | |
| 20 µg | $163 | - | In Stock | |
| 50 µg | $320 | - | In Stock | |
| 100 µg | $567 | 7-10 days | 7-10 days | |
| 200 µg | $1,000 | 7-10 days | 7-10 days | |
| 500 µg | $2,120 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:95.9%
Appearance:Lyophilized powder
Color:White
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Product Information
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Measured by its ability to hydrolyze the 5’phosphategroups from the substrate adenosine 5’triphosphate(ATP). The specific activity is > 5000 pmoles/min/μg. |
| Description | CD39 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 51.8 kDa and the accession number is XP_015311944.1&XP_015003298.1. |
| Species | Cynomolgus,Rhesus |
| Expression System | Baculovirus Insect Cells |
| Tag | C-His |
| Accession Number | XP_015311944.1&XP_015003298.1 |
| Construction | A DNA sequence encoding the cynomolgus / rhesus ENTPD1 (XP_015311944.1/XP_015003298.1) (Thr60-Val500) was expressed with a polyhistidine tag at the C-terminus. Cynomolgus and Rhesus ENTPD1 sequences are identical. Predicted N terminal: Thr 60 |
| Protein Purity | > 90 % as determined by SDS-PAGE.  |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris, 300 mM NaCl, 10% glycerol, pH 7.5. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstituted with sterile deionized water to 0.2 mg/mL. Reconstitution conditions may vary depending on the lot. |
| Synonyms | ectonucleoside triphosphate diphosphohydrolase 1 |
| Research Background | CD39, also known as ENTPD1, belongs to the GDA1/CD39 NTPase family. It is expressed primarily on activated lymphoid cells and can also be detected in endothelial tissues. The vascular isoform and the placental isoform II are present in both placenta and umbilical vein, whereas placental isoform I is present in placenta only. CD39 can hydrolyze both nucleoside triphosphates and diphosphates. It is the dominant ecto nucleotidase of vascular and placental trophoblastic tissues and appears to modulate the functional expression of type 2 purinergic (P2) G protein coupled receptors (GPCRs). CD39 transgenic mice exhibit impaired platelet aggregation, prolonged bleeding times, and resistance to systemic thromboembolism. There is a correlation between ATP hydrolysis and triglycerides in patients with chronic heart disease, suggesting a relationship between ATP diphosphohydrolase and thrombogenesis. In the nervous system, CD39 could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. |
| Molecular Weight | 51.8 kDa (predicted) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: CD39 Protein, Cynomolgus, Rhesus, Recombinant (His) chemical structure | CD39 Protein, Cynomolgus, Rhesus, Recombinant (His) molecular weight
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