AKR1C2 Protein, Human, Recombinant

Catalog No. TMPJ-00207 Copy Product Info

Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-α/5-β-Steroid Reductases to convert Steroid hormones into the 3-α/5-α and 3-α/5-β-Tetrahydrosteroids. AKR1C2 catalyzes the inactivation of the most potent androgen 5-α-Dihydrotestosterone (5-α-DHT) to 5-α-Androstane-3-α, 17-β-diol (3-α-diol).

AKR1C2 Protein, Human, Recombinant

Catalog No. TMPJ-00207

Copy Product Info

Pack Size	Price	USA Stock	Global Stock
5 μg	$112	2-4 weeks	2-4 weeks
10 μg	$183	2-4 weeks	2-4 weeks
20 μg	$292	2-4 weeks	2-4 weeks
50 μg	$545	2-4 weeks	2-4 weeks
100 μg	$792	2-4 weeks	2-4 weeks
200 μg	$1,150	2-4 weeks	2-4 weeks
500 μg	$1,900	2-4 weeks	2-4 weeks
1 mg	$2,730	2-4 weeks	2-4 weeks

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For In stock only · Estimated delivery:USA Stock (1-2 days) Global Stock (5-7 days)

For research use only—not for human use. No sales to individuals. Use as intended only.

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Biological Activity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-α/5-β-Steroid Reductases to convert Steroid hormones into the 3-α/5-α and 3-α/5-β-Tetrahydrosteroids. AKR1C2 catalyzes the inactivation of the most potent androgen 5-α-Dihydrotestosterone (5-α-DHT) to 5-α-Androstane-3-α, 17-β-diol (3-α-diol).
Species	Human
Expression System	E. coli
Tag	Tag Free
Accession Number	P52895
Synonyms	Type III 3-,Trans-1,Dihydrodiol Dehydrogenase/Bile Acid-Binding Protein,Dihydrodiol Dehydrogenase 2,DD-2,DD2,DD/BABP,Chlordecone Reductase Homolog HAKRD,Aldo-Keto Reductase Family 1 Member C2,3-α-HSD3,3-Alpha-HSD3,2-Diol Dehydrogenase,2-Dihydrobenzene-1
Amino Acid	Met1-Tyr323
Construction	Met1-Tyr323
Protein Purity	Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight	35 KDa (reducing condition)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 100 mM NaCl, 1 mM DTT, pH 8.0.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Proteins are shipped with blue ice.
Research Background	Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-α/5-β-Steroid Reductases to convert Steroid hormones into the 3-α/5-α and 3-α/5-β-Tetrahydrosteroids. AKR1C2 catalyzes the inactivation of the most potent androgen 5-α-Dihydrotestosterone (5-α-DHT) to 5-α-Androstane-3-α, 17-β-diol (3-α-diol).