AKR1C2 Protein, Human, Recombinant

Name: AKR1C2 Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPJ-00207
Rating: 4.5 (1 reviews)

(Synonyms: Type III 3-, Trans-1, Dihydrodiol Dehydrogenase/Bile Acid-Binding Protein, Dihydrodiol Dehydrogenase 2, DD-2, DD2, DD/BABP, Chlordecone Reductase Homolog HAKRD, Aldo-Keto Reductase Family 1 Member C2, 3-α-HSD3, 3-Alpha-HSD3, 2-Diol Dehydrogenase, 2-Dihydrobenzene-1) Copy Product Info

Synonyms: Type III 3-, Trans-1, Dihydrodiol Dehydrogenase/Bile Acid-Binding Protein, Dihydrodiol Dehydrogenase 2, DD-2, DD2, DD/BABP, Chlordecone Reductase Homolog HAKRD, Aldo-Keto Reductase Family 1 Member C2, 3-α-HSD3, 3-Alpha-HSD3, 2-Diol Dehydrogenase, 2-Dihydrobenzene-1

Catalog No. TMPJ-00207 Copy Product Info

Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-α/5-β-Steroid Reductases to convert Steroid hormones into the 3-α/5-α and 3-α/5-β-Tetrahydrosteroids. AKR1C2 catalyzes the inactivation of the most potent androgen 5-α-Dihydrotestosterone (5-α-DHT) to 5-α-Androstane-3-α, 17-β-diol (3-α-diol).

Pack Size	Price	USA Stock	Global Stock
10 µg	$183	35 days	35 days
20 µg	$292	35 days	35 days
50 µg	$545	35 days	35 days
100 µg	$792	35 days	35 days
200 µg	$1,150	35 days	35 days
500 µg	$1,900	35 days	35 days
1 mg	$2,730	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-α/5-β-Steroid Reductases to convert Steroid hormones into the 3-α/5-α and 3-α/5-β-Tetrahydrosteroids. AKR1C2 catalyzes the inactivation of the most potent androgen 5-α-Dihydrotestosterone (5-α-DHT) to 5-α-Androstane-3-α, 17-β-diol (3-α-diol).
Species	Human
Expression System	E. coli
Tag	Tag Free
Accession Number	P52895
Amino Acid	Met1-Tyr323
Construction	Met1-Tyr323
Protein Purity	Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 100 mM NaCl, 1 mM DTT, pH 8.0.
Synonyms	Type III 3-, Trans-1, Dihydrodiol Dehydrogenase/Bile Acid-Binding Protein, Dihydrodiol Dehydrogenase 2, DD-2, DD2, DD/BABP, Chlordecone Reductase Homolog HAKRD, Aldo-Keto Reductase Family 1 Member C2, 3-α-HSD3, 3-Alpha-HSD3, 2-Diol Dehydrogenase, 2-Dihydrobenzene-1
Research Background	Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-α/5-β-Steroid Reductases to convert Steroid hormones into the 3-α/5-α and 3-α/5-β-Tetrahydrosteroids. AKR1C2 catalyzes the inactivation of the most potent androgen 5-α-Dihydrotestosterone (5-α-DHT) to 5-α-Androstane-3-α, 17-β-diol (3-α-diol).

Chemical Properties

Molecular Weight

35 KDa (reducing condition)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.