Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-α/5-β-Steroid Reductases to convert Steroid hormones into the 3-α/5-α and 3-α/5-β-Tetrahydrosteroids. AKR1C2 catalyzes the inactivation of the most potent androgen 5-α-Dihydrotestosterone (5-α-DHT) to 5-α-Androstane-3-α, 17-β-diol (3-α-diol).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 μg | 5 days | $ 184.00 | |
50 μg | 5 days | $ 545.00 | |
500 μg | 5 days | $ 1,900.00 | |
1 mg | 5 days | $ 2,730.00 |
Description | Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-α/5-β-Steroid Reductases to convert Steroid hormones into the 3-α/5-α and 3-α/5-β-Tetrahydrosteroids. AKR1C2 catalyzes the inactivation of the most potent androgen 5-α-Dihydrotestosterone (5-α-DHT) to 5-α-Androstane-3-α, 17-β-diol (3-α-diol). |
Species | Human |
Expression System | E. coli |
Tag | None |
Accession Number | P52895 |
Synonyms | 3-Alpha-HSD3, Chlordecone Reductase Homolog HAKRD, 2-Diol Dehydrogenase, Dihydrodiol Dehydrogenase 2, DD/BABP, Type III 3-, 2-Dihydrobenzene-1, DD2, Trans-1, Aldo-Keto Reductase Family 1 Member C2, DD-2, Dihydrodiol Dehydrogenase/Bile Acid-Binding Protein, 3-α-HSD3 |
Amino Acid | Met1-Tyr323 |
Construction | Recombinant Human Aldo-Keto Reductase Family 1 Member C2 is produced by our E.coli expression system and the target gene encoding Met1-Tyr323 is expressed. |
Protein Purity | Greater than 90% as determined by reducing SDS-PAGE. (QC verified) |
Molecular Weight | 35 KDa, reducing conditions |
Endotoxin | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 1mM DTT, pH 8.0. |
Stability & Storage |
Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
Shipping |
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below. |
Research Background | Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-α/5-β-Steroid Reductases to convert Steroid hormones into the 3-α/5-α and 3-α/5-β-Tetrahydrosteroids. AKR1C2 catalyzes the inactivation of the most potent androgen 5-α-Dihydrotestosterone (5-α-DHT) to 5-α-Androstane-3-α, 17-β-diol (3-α-diol). |
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AKR1C2 Protein, Human, Recombinant 3-Alpha-HSD3 Chlordecone Reductase Homolog HAKRD 2-Diol Dehydrogenase Dihydrodiol Dehydrogenase 2 DD/BABP DD 2 Type III 3- 2-Dihydrobenzene-1 DD2 Trans-1 Aldo-Keto Reductase Family 1 Member C2 DD-2 Dihydrodiol Dehydrogenase/Bile Acid-Binding Protein 3-a-HSD3 3-α-HSD3 recombinant recombinant-proteins proteins protein