Bovine coronavirus (strain Mebus) Hemagglutinin-esterase Protein (His)

Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.

Bovine coronavirus (strain Mebus) Hemagglutinin-esterase Protein (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 47.7 kDa and the accession number is P15776.

Bovine

P. pastoris (Yeast)

> 90% as determined by SDS-PAGE.

Structural protein that makes short spikes at the surface of the virus. Contains receptor binding and receptor-destroying activities. Mediates de-O-acetylation of N-acetyl-4-O-acetylneuraminic acid, which is probably the receptor determinant recognized by the virus on the surface of erythrocytes and susceptible cells. This receptor-destroying activity is important for virus release as it probably helps preventing self-aggregation and ensures the efficient spread of the progeny virus from cell to cell. May serve as a secondary viral attachment protein for initiating infection, the spike protein being the major one. May become a target for both the humoral and the cellular branches of the immune system.