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Cytidine 5′-diphosphate
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Catalog No. T8735Cas No. 63-38-7
Alias Cytidine diphosphate, Cytidine coenzyme, Cytidine 5′-pyrophosphate, CDP, 5'-CDP
Cytidine 5′-diphosphat (5'-CDP) is synthesized from cytidine monophosphate (CMP) or uridine monophosphate (UMP) by the transfer of phosphoryl group, catalyzed by the enzyme uridylate kinase (UMPK).
Cytidine 5′-diphosphate
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Purity: 99.50%
Catalog No. T8735Alias Cytidine diphosphate, Cytidine coenzyme, Cytidine 5′-pyrophosphate, CDP, 5'-CDPCas No. 63-38-7
Cytidine 5′-diphosphat (5'-CDP) is synthesized from cytidine monophosphate (CMP) or uridine monophosphate (UMP) by the transfer of phosphoryl group, catalyzed by the enzyme uridylate kinase (UMPK).
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 5 mg | $50 | In Stock | In Stock | |
| 10 mg | $75 | In Stock | In Stock | |
| 25 mg | $128 | In Stock | In Stock | |
| 50 mg | $192 | - | In Stock | |
| 100 mg | $287 | - | In Stock | |
| 200 mg | $431 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.50%
Appearance:Viscous
Color:White
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Product Introduction
Cytidine 5′-diphosphate AI Summary
Cytidine 5′-diphosphate exhibits a range of bioactivities across different targets. It inhibits the rate of UDP-GlcNAc import into the lumen of Golgi membranes with an IC50 value of 100,000 nM and leads to an accumulation of UDP-GlcNAc in this region with an IC50 value of 5000 nM. It also acts as a time-dependent inactivator of ribonucleotide diphosphate reductase (RDPR) in Escherichia coli, displaying a Km value of 50,000 nM and a Vmax of 1200 nM min-1 mg-1. Additionally, it functions as an agonist at the human recombinant P2Y6 receptor in 1321N1 cells, promoting PLC-mediated [3H]IP production with a stronger affinity for the P2Y2 receptor (Ratio EC50 of 110 versus 1000 for P2Y6) and an EC50 value of 88,000 nM for P2Y6 activation. Furthermore, it shows bioactivity on NDPK expressed in HepG2 cells with a Km of 307,000 nM and a kcat/Km of 0.6 /uM/s, and a Kcat value of 183 /s. It has a binding affinity to Burkholderia pseudomallei IspF with a Kd value of 75,000 nM by surface plasmon resonance. Lastly, it inhibits E. coli IspF-MEP complex at 700 uM with a 46% inhibition rate after 30 minutes of pre-incubation and inhibits E. coli IspF with an IC50 value of 768,000 nM according to an HPLC-based cAMP formation assay..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Cytidine 5′-diphosphat (5'-CDP) is synthesized from cytidine monophosphate (CMP) or uridine monophosphate (UMP) by the transfer of phosphoryl group, catalyzed by the enzyme uridylate kinase (UMPK). |
| Synonyms | Cytidine diphosphate, Cytidine coenzyme, Cytidine 5′-pyrophosphate, CDP, 5'-CDP |
| Molecular Weight | 403.18 |
| Formula | C9H15N3O11P2 |
| Cas No. | 63-38-7 |
| Smiles | Nc1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)n1 |
| Relative Density. | 2.35g/cm3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO: Slightly soluble  |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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