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Hyaluronidase 2/HYAL2 Protein, Human, Recombinant (His)

Catalog No. TMPK-00954
Synonyms: LuCa-2, Hyaluronidase 2, LUCA2, HYAL2, Hyal-2, Hyaluronidase-2

Hyaluronidases, a family of enzymes that are able to degrade hyaluronic acid (HA), are employed in medicine to increase drug diffusion and reverse the effects of HA filler injections. Hyaluronidases are able to dissolve subcutaneous nodules or to correct excessive quantities of injected filler. Upregulation of hyaluronidase 2 (HYAL2), one of somatic hyaluronidase (HAase), was demonstrated in granulation tissue during the healing of equine superficial digital flexor tendon injuries.

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Hyaluronidase 2/HYAL2 Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 418.00
500 μg 5 days $ 1,670.00
1 mg 5 days $ 2,800.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description Hyaluronidases, a family of enzymes that are able to degrade hyaluronic acid (HA), are employed in medicine to increase drug diffusion and reverse the effects of HA filler injections. Hyaluronidases are able to dissolve subcutaneous nodules or to correct excessive quantities of injected filler. Upregulation of hyaluronidase 2 (HYAL2), one of somatic hyaluronidase (HAase), was demonstrated in granulation tissue during the healing of equine superficial digital flexor tendon injuries.
Species Human
Expression System HEK293
Tag C-His
Accession Number Q12891
Synonyms LuCa-2, Hyaluronidase 2, LUCA2, HYAL2, Hyal-2, Hyaluronidase-2
Construction Recombinant Human Hyaluronidase 2/HYAL2 Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Met21-Gly447.[Accession |Q12891]
Protein Purity > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight The protein has a predicted MW of 49.22 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
Endotoxin Less than 1EU per μg by the LAL method.
Formulation Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Stability & Storage

Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background Hyaluronidases, a family of enzymes that are able to degrade hyaluronic acid (HA), are employed in medicine to increase drug diffusion and reverse the effects of HA filler injections. Hyaluronidases are able to dissolve subcutaneous nodules or to correct excessive quantities of injected filler. Upregulation of hyaluronidase 2 (HYAL2), one of somatic hyaluronidase (HAase), was demonstrated in granulation tissue during the healing of equine superficial digital flexor tendon injuries.

References and Literature

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Keywords

Hyaluronidase 2/HYAL2 Protein, Human, Recombinant (His) LuCa-2 Hyaluronidase 2 LUCA2 HYAL2 LUCA 2 Hyal-2 HYAL 2 Hyaluronidase-2 LUCA-2 recombinant recombinant-proteins proteins protein

 

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