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Anti-NGFR/p75NTR Antibody (2N149)

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Catalog No. TMAC-03038

Anti-NGFR/p75NTR Antibody (2N149) is a Rabbit antibody targeting NGFR/p75NTR. Anti-NGFR/p75NTR Antibody (2N149) can be used in WB,ICC/IF,IHC,IP.

Anti-NGFR/p75NTR Antibody (2N149)

Anti-NGFR/p75NTR Antibody (2N149)

😃Good
Catalog No. TMAC-03038
Anti-NGFR/p75NTR Antibody (2N149) is a Rabbit antibody targeting NGFR/p75NTR. Anti-NGFR/p75NTR Antibody (2N149) can be used in WB,ICC/IF,IHC,IP.
Pack SizePriceAvailabilityQuantity
50 μL$2977-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-NGFR/p75NTR Antibody (2N149) is a Rabbit antibody targeting NGFR/p75NTR. Anti-NGFR/p75NTR Antibody (2N149) can be used in WB,ICC/IF,IHC,IP.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe Trk oncogene encodes a membrane-spanning protein tyrosine kinase, gp140Trk, whose expression is restricted in vivo to neurons of the sensory spinal and cranial ganglia of neural crest origin. Nerve growth factor (NGF) stimulates tyrosine phosphorylation of Trk A in neural cell lines and in embryonic dorsal root ganglia. Tyrosine phosphorylation of Trk by NGF is rapid, specific and occurs with picomolar quantities of factor, indicating that the response is mediated by physiological amounts of NGF, suggesting that Trk A participates in the primary signal transduction mechanism of NGF. An additional component of the Trk A receptor complex, NGFR p75, binds to the neurotrophic factors with low affinity but is required for efficient signaling. NGFR p75 accelerates Trk A activation and may recruit downstream effector molecules to the liganded complex.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 75 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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