Powder: -20°C for 3 years | In solvent: -80°C for 1 year
T-705RMP, the phosphorylated metabolite derived from T-705, demonstrates a limited inhibitory impact on the host cells' IMP dehydrogenase (IMPDH) activities, with an IC 50 value of 601 μM.
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25 mg | Inquiry | $ 1,520.00 |
Description | T-705RMP, the phosphorylated metabolite derived from T-705, demonstrates a limited inhibitory impact on the host cells' IMP dehydrogenase (IMPDH) activities, with an IC 50 value of 601 μM. |
In vitro | T-705 undergoes phosphorylation by cellular kinases to form T-705RMP and T-705RTP; enzymes within the host cell can distinguish between T-705, its phosphorylated forms (T-705RMP and T-705RTP), and natural nucleotides. Notably, T-705RMP inhibits IMPDH approximately 150-fold less effectively than Ribavirin monophosphate, indicating that T-705's antiviral activity does not stem from inhibiting this cellular enzyme[1]. |
Molecular Weight | 369.198 |
Formula | C10H13FN3O9P |
CAS No. | 356783-08-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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T-705RMP 356783-08-9 T705RMP T 705RMP inhibitor inhibit