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Anti-PRTFDC1 Antibody (1M206)

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Catalog No. TMAY-02683
Alias PRTFDC1, phosphoribosyl transferase domain containing 1, HHGP

Anti-PRTFDC1 Antibody (1M206) is a Rabbit antibody targeting PRTFDC1. Anti-PRTFDC1 Antibody (1M206) can be used in ELISA.

Anti-PRTFDC1 Antibody (1M206)

Anti-PRTFDC1 Antibody (1M206)

😃Good
Catalog No. TMAY-02683Alias PRTFDC1, phosphoribosyl transferase domain containing 1, HHGP
Anti-PRTFDC1 Antibody (1M206) is a Rabbit antibody targeting PRTFDC1. Anti-PRTFDC1 Antibody (1M206) can be used in ELISA.
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100 μL$268 7-10 days
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Product Introduction

Bioactivity
Description
Anti-PRTFDC1 Antibody (1M206) is a Rabbit antibody targeting PRTFDC1. Anti-PRTFDC1 Antibody (1M206) can be used in ELISA.
AliasPRTFDC1, phosphoribosyl transferase domain containing 1, HHGP
Ig Type
Monoclonal Rabbit IgG
Clone
1M206
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human PRTFDC1 (rh PRTFDC1; TMPY-03332; Q9NRG1-1; Met1-Val225).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundPRTFDC1 is a member of the purine/pyrimidine phosphoribosyltransferase family. It can bind GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). The epigenetic silencing of PRTFDC1 by hypermethylation of the CpG island leads to a loss of PRTFDC1 function, which might be involved in squamous cell oral carcinogenesis. PRTFDC1 is a genetic modifier of HPRT-deficiency in the mouse and has important implications for unraveling the molecular etiology of lesch-Nyhan disease(LND). LND is a severe X-linked neurological disorder caused by a deficiency of hypoxanthine phosphoribosyltransferase. PRTFDC1 has a low, barely measurable phosphoribosyltransferase activity (in vitro).
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human PRTFDC1 Protein (TMPY-03332)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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