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Anti-PFKFB3 Antibody (1B165)

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Catalog No. TMAC-03170

Anti-PFKFB3 Antibody (1B165) is a Rabbit antibody targeting PFKFB3. Anti-PFKFB3 Antibody (1B165) can be used in WB,ICC,IHC,FCM,IP.

Anti-PFKFB3 Antibody (1B165)

Anti-PFKFB3 Antibody (1B165)

😃Good
Catalog No. TMAC-03170
Anti-PFKFB3 Antibody (1B165) is a Rabbit antibody targeting PFKFB3. Anti-PFKFB3 Antibody (1B165) can be used in WB,ICC,IHC,FCM,IP.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-PFKFB3 Antibody (1B165) is a Rabbit antibody targeting PFKFB3. Anti-PFKFB3 Antibody (1B165) can be used in WB,ICC,IHC,FCM,IP.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundAmong the enzymes playing role in glycolysis,four allosteric PFKFB enzymes 1?C4 expressed by four independent PFKFB genes, catalyze the rate-limiting phosphorylation of fructose-6-phosphate to fructose-1, 6-bisphosphate, using ATP as the energy source in the glycolysis pathway. Among these four allosteric enzymes, PFKFB3 enzyme retains the highest Kinase/Biphosphatase activity ratio and is expressed by PFKFB3 gene which has been demonstrated to be highly expressed in leukemic cells and in solid tumors. Moreover, mitogenic, hypoxic and inflammatory conditions have an inductive effect on the expression of PFKFB3. Hence upregulation of PFKFB genes specific to cancer cells compared to their normal counterparts (from the same patients) with more robust over-expression in breast and lung cancer make it a more appropriate target.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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