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Oncostatin M/OSM Protein, Human, Recombinant (E. coli)
(Synonyms: oncostatin M, OncoM) Copy Product InfoSynonyms: oncostatin M, OncoM
Catalog No. TMPS-00167 Copy Product Info
Oncostatin M/OSM Protein, Human, Recombinant (E. coli) is expressed in E. coli. The accession number is P13725.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $98 | 7-10 days | 7-10 days | |
| 10 µg | $170 | 7-10 days | 7-10 days | |
| 20 µg | $295 | 7-10 days | 7-10 days | |
| 50 µg | $622 | 7-10 days | 7-10 days | |
| 100 µg | $993 | 7-10 days | 7-10 days | |
| 200 µg | $1,580 | 7-10 days | 7-10 days | |
| 500 µg | $2,960 | 7-10 days | 7-10 days | |
| 1 mg | $4,750 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | ED 50 < 10.0 ng/ml, measured by a cell proliferation assay using TF-1 cells, corresponding to a specific activity of > 1.0 × 10 5 units/mg. |
| Description | Oncostatin M/OSM Protein, Human, Recombinant (E. coli) is expressed in E. coli. The accession number is P13725. |
| Species | Human |
| Expression System | E. coli |
| Tag | Tag Free |
| Accession Number | P13725 |
| Construction | Ala26-Arg234 |
| Protein Purity | > 95% as determined by SDS-PAGE; > 95% as determined by HPLC |
| Endotoxin | < 0.2 EU/μg of protein as determined by the LAL method. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS. |
| Reconstitution | Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | oncostatin M, OncoM |
| Research Background | Oncostatin M (OSM) is a multifunctional cytokine, and belongs to Interleukin-6 (IL-6) subfamily, which also includes IL-11, leukemia inhibitory factor (LIF), ciliary neurotropic factor, cardiotrophin-1, and novel neurotropin-1. In vivo, OSM is secreted from activated T cells, monocytes, neutrophils, and endothelial cells. OSM is related to LIF, and shares a receptor with LIF in human. Human OSM can bind to gp130 and recruit OSM Receptor β or LIF Receptor β to form a ternary complex. OSM stimulates the growth of different types of cells, including megakaryocytes, fibroblasts, vascular endothelial cells, and T cells. OSM inhibits the proliferation of several cancer cell lines, such as solid tissue tumor cells, lung cancer cells, melanoma cells, and breast cancer cells. |
| Molecular Weight | ~23.8 kDa (Reducing conditions) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles. |
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Related Tags: Oncostatin M/OSM Protein, Human, Recombinant (E. coli) chemical structure | Oncostatin M/OSM Protein, Human, Recombinant (E. coli) molecular weight
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