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Depemokimab
(Synonyms: GSK-3511294, GSK3511294) Copy Product Info
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Synonyms: GSK-3511294, GSK3511294
Catalog No. T77156 Copy Product Info
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Depemokimab (GSK-3511294) is a long-acting anti-IL-5 monoclonal antibody. Depemokimab (GSK-3511294) is utilized in immunology and respiratory disease research focused on IL-5 signaling inhibition, eosinophil-associated inflammatory pathways, and cytokine-targeted modulation in asthma-related model systems.
Cas No. 2243274-14-6
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $247 | - | In Stock | |
| 5 mg | $747 | - | In Stock | |
| 10 mg | $1,200 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:98.1% (SDS-PAGE); 98.1% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
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Chemical Properties
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| Description | Depemokimab (GSK-3511294) is a long-acting anti-IL-5 monoclonal antibody. Depemokimab (GSK-3511294) is utilized in immunology and respiratory disease research focused on IL-5 signaling inhibition, eosinophil-associated inflammatory pathways, and cytokine-targeted modulation in asthma-related model systems. |
| In vitro | Methods：Pharmacokinetic studies were conducted in cynomolgus monkeys to compare the clearance rate and IL-5 binding affinity between Depemokimab and mepolizumab. Results：Compared with mepolizumab, Depemokimab had approximately 2-fold lower clearance rate and around 30-fold higher binding affinity for IL-5 [2]. |
| Synonyms | GSK-3511294, GSK3511294 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | IL-5 |
| Molecular Weight | 146.05 kDa (Predicted) |
| Cas No. | 2243274-14-6 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature, -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: Depemokimab chemical structure | Depemokimab in vitro | Depemokimab molecular weight
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