Select your Country or Region

  • TargetMol | Compound LibraryArgentinaArgentina
  • TargetMol | Compound LibraryAustraliaAustralia
  • TargetMol | Compound LibraryAustriaAustria
  • TargetMol | Compound LibraryBelgiumBelgium
  • TargetMol | Compound LibraryBrazilBrazil
  • TargetMol | Compound LibraryBulgariaBulgaria
  • TargetMol | Compound LibraryCroatiaCroatia
  • TargetMol | Compound LibraryCyprusCyprus
  • TargetMol | Compound LibraryCzechCzech
  • TargetMol | Compound LibraryDenmarkDenmark
  • TargetMol | Compound LibraryEgyptEgypt
  • TargetMol | Compound LibraryEstoniaEstonia
  • TargetMol | Compound LibraryFinlandFinland
  • TargetMol | Compound LibraryFranceFrance
  • TargetMol | Compound LibraryGermanyGermany
  • TargetMol | Compound LibraryGreeceGreece
  • TargetMol | Compound LibraryHong KongHong Kong
  • TargetMol | Compound LibraryHungaryHungary
  • TargetMol | Compound LibraryIcelandIceland
  • TargetMol | Compound LibraryIndiaIndia
  • TargetMol | Compound LibraryIrelandIreland
  • TargetMol | Compound LibraryIsraelIsrael
  • TargetMol | Compound LibraryItalyItaly
  • TargetMol | Compound LibraryJapanJapan
  • TargetMol | Compound LibraryKoreaKorea
  • TargetMol | Compound LibraryLatviaLatvia
  • TargetMol | Compound LibraryLebanonLebanon
  • TargetMol | Compound LibraryMalaysiaMalaysia
  • TargetMol | Compound LibraryMaltaMalta
  • TargetMol | Compound LibraryMoroccoMorocco
  • TargetMol | Compound LibraryNetherlandsNetherlands
  • TargetMol | Compound LibraryNew ZealandNew Zealand
  • TargetMol | Compound LibraryNorwayNorway
  • TargetMol | Compound LibraryPolandPoland
  • TargetMol | Compound LibraryPortugalPortugal
  • TargetMol | Compound LibraryRomaniaRomania
  • TargetMol | Compound LibrarySingaporeSingapore
  • TargetMol | Compound LibrarySlovakiaSlovakia
  • TargetMol | Compound LibrarySloveniaSlovenia
  • TargetMol | Compound LibrarySpainSpain
  • TargetMol | Compound LibrarySwedenSweden
  • TargetMol | Compound LibrarySwitzerlandSwitzerland
  • TargetMol | Compound LibraryTaiwan,ChinaTaiwan,China
  • TargetMol | Compound LibraryThailandThailand
  • TargetMol | Compound LibraryTurkeyTurkey
  • TargetMol | Compound LibraryUnited KingdomUnited Kingdom
  • TargetMol | Compound LibraryUnited StatesUnited States
  • TargetMol | Compound LibraryOther CountriesOther Countries
Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Filter
TargetMol | Tags Immunology/Inflammation
TargetMol | Tags Metabolism

AhR

The aryl hydrocarbon receptor (AHR) is a member of the basic helix-loop-helix-period-aryl hydrocarbon receptor nuclear translocator-single-minded (bHLH-PAS) family of transcription factors, which act as biological sensors by initiating gene expression programs in response to endogenous and exogenous signals.

  • Nimodipine
    T034366085-59-4
    Nimodipine (BAY-e 9736), a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.
    • $40
    In Stock
    Size
    QTY
    TargetMol | Citations Cited
  • WAY-605471
    T9822378223-81-5
    WAY-605471 is a AHR antagonist with IC50 of 0.5 - 1 μM.
    • $117
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • Phortress
    T23151328087-38-3In house
    Phortress (NSC-710305) is a potent AhR ligand with strong binding affinity, which subsequently triggers the transcription of CYP1A1 and induces antitumor activity.
    • $30
    In Stock
    Size
    QTY
  • StemRegenin 1
    T18311227633-49-9
    StemRegenin 1 (SR1) is an aryl hydrocarbon receptor (AhR) inhibitor.
    • $32
    In Stock
    Size
    QTY
    TargetMol | Citations Cited
  • Tapinarof
    T464479338-84-4
    Tapinarof (Benvitimod) is targeted as a topical cream treatment for psoriasis, a chronic autoimmune skin disease.
    • $34
    In Stock
    Size
    QTY
    TargetMol | Citations Cited
  • CH-223191
    T2448301326-22-7
    CH-223191 is a potent and specific antagonist for aryl hydrocarbon receptor (AhR).
    • $56
    In Stock
    Size
    QTY
    TargetMol | Citations Cited
  • YL-109
    T196036341-25-0
    YL-109, a novel anticancer agent, can inhibit breast Y cell growth and invasiveness in vitro and in vivo.
    • $30
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • PDM11
    T55411032508-03-4
    PDM11 (1-[2-(4-Chloro-phenyl)-vinyl]-3,5-diMeth) is an antagonist of aryl hydrocarbon receptor (AhR)
    • $70
    In Stock
    Size
    QTY
    TargetMol | Inhibitor Sale
  • 1,4-Chrysenequinone
    T10007100900-16-1
    1,4-Chrysenequinone (Chrysene-1,4-dione) is an activator of aryl hydrocarbon receptor (AhR).
    • $30
    In Stock
    Size
    QTY
  • Prochloraz
    T2062567747-09-5
    Prochloraz (Prelude) is a broad-spectrum contact imidazole fungicide. Prochloraz inhibits human placental microsomal aromatase in vitro (IC50 = 40 nM). Prochloraz also acts as an estrogen receptor (IC50s = 25 μM) and androgen receptor (IC50 = 4 μM) antagonist, and activates aryl hydrocarbon receptors (EC50 = 1 μM).
    • $34
    In Stock
    Size
    QTY
  • ITE
    T7202448906-42-1
    ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) (Ki : 3 nM), has immunosuppressive activity.
    • $34
    In Stock
    Size
    QTY
  • D-Kynurenine
    T1093813441-51-5
    D-Kynurenine (ZINC901103) is a metabolite of D-tryptophan and an agonist of GPR109B. D-Kynurenine activates AhR and promotes the conversion of the epithelium to mesenchyme. D-Kynurenine serves as a substrate in the fluorescence analysis of D-amino acid oxidase.
    • $48
    In Stock
    Size
    QTY
  • CAY 10465
    T4607688348-33-6
    CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM).
    • $30
    In Stock
    Size
    QTY
  • BAY-218
    T56222162982-11-6
    BAY-218 (AHR antagonist 1) is an aryl hydrocarbon receptor (AHR) antagonist , has an IC50 of 39.9 nM in human cell line.
    • $34
    In Stock
    Size
    QTY
  • (-)-Perillaldehyde
    T911218031-40-8
    (-)-Perillaldehyde shows antibacterial activity.
    • $30
    In Stock
    Size
    QTY
  • Brevifolincarboxylic acid
    TN145118490-95-4
    Brevifolincarboxylic acid is a natural product isolated from Polygonum capitatum, it has inhibitory effect on the aryl hydrocarbon receptor (AhR). Brevifolincarboxylic acid is an α-glucosidase inhibitor with an IC50 of 323.46 μM.
    • $77
    In Stock
    Size
    QTY
  • Skatole
    T528183-34-1
    Skatole (3-Methyl-1H-indole) is produced by intestinal bacteria. Skatole regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.
    • $29
    In Stock
    Size
    QTY
  • L-Kynurenine
    T49282922-83-0
    L-Kynurenine ((S)-Kynurenine) is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppression of antitumor immune responses. It has been shown to inhibit allogeneic T-cell proliferation and to increase malignant U87 glioma cell invasion into a collagen matrix.
    • $30
    In Stock
    Size
    QTY
  • PDM2
    T4608688348-25-6
    PDM 2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist.
    • $42
    In Stock
    Size
    QTY
  • Leflunomide
    T115975706-12-6
    Leflunomide (HWA486) is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis.
    • $39
    In Stock
    Size
    QTY
  • Potassium 1H-indol-3-yl sulfate
    T49382642-37-7
    Potassium 1H-indol-3-yl sulfate (Potassium 3-indoxyl sulfate) is an agonist for the human Aryl Hydrocarbon Receptor (AhR). The Aryl Hydrocarbon Receptor (AhR) has recently emerged as a pathophysiological regulator of immune-inflammatory conditions and potassium 1H-indol-3-yl sulfate has been shown to be a ligand for AhR. Potassium 1H-indol-3-yl sulfate is also a metabolite of tryptophan derived from dietary protein. Tryptophan is metabolized by intestinal bacteria into indole, which is absorbed into the blood and then further metabolized to indoxyl sulfate in the liver, which is normally excreted in urine. In chronic kidney disease patients where renal function is compromised, potassium 1H-indol-3-yl sulfate can accumulate in serum as a uremic toxin, inducing oxidative stress and accelerating progression of the disease. Potassium 1H-indol-3-yl sulfate at 250 μM can induce the activation of NF-Κb, promoting the expression of both TGF-β1 and Smad3 expression in proximal tubular cells of rats, which is associated with profibrotic activity.
    • $34
    In Stock
    Size
    QTY
  • Mexiletine hydrochloride
    T10465370-01-4
    Mexiletine hydrochloride (KOE-1173 hydrochloride) is a voltage-gated sodium channel blocker and a Class IB antiarrhythmic drug. Mexiletine hydrochloride exerts antiarrhythmic effects by inhibiting sodium current in myocardial cells, thereby reducing the rise rate of cardiac action potential (phase 0) and reducing the automaticity of Purkinje fibers.
    • $35
    In Stock
    Size
    QTY