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Anti-MCP-1/CCL2 Polyclonal Antibody
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Catalog No. TMAB-01115
Alias Small-inducible cytokine A2, Scya2, Monocyte chemotactic protein 1, Monocyte chemoattractant protein 1, MCP-1, Ccl2, C-C motif chemokine 2
Anti-MCP-1/CCL2 Polyclonal Antibody is a Rabbit antibody targeting MCP-1/CCL2. Anti-MCP-1/CCL2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Anti-MCP-1/CCL2 Polyclonal Antibody
Anti-MCP-1/CCL2 Polyclonal Antibody
😃Good
Catalog No. TMAB-01115Alias Small-inducible cytokine A2, Scya2, Monocyte chemotactic protein 1, Monocyte chemoattractant protein 1, MCP-1, Ccl2, C-C motif chemokine 2
Anti-MCP-1/CCL2 Polyclonal Antibody is a Rabbit antibody targeting MCP-1/CCL2. Anti-MCP-1/CCL2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $221 | 7-10 days | |
| 100 μL | $372 | 7-10 days | |
| 200 μL | $527 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-MCP-1/CCL2 Polyclonal Antibody is a Rabbit antibody targeting MCP-1/CCL2. Anti-MCP-1/CCL2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF. |
| Alias | Small-inducible cytokine A2, Scya2, Monocyte chemotactic protein 1, Monocyte chemoattractant protein 1, MCP-1, Ccl2, C-C motif chemokine 2 |
| Ig Type | IgG |
| Reactivity | Rat |
| Verified Activity | 1. Tissue/cell: mouse kidney tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-MCP-1 Polyclonal Antibody, Unconjugated (TMAB-01115) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining. 2. Paraformaldehyde-fixed, paraffin embedded (rat lung); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (MCP1) Polyclonal Antibody, Unconjugated (TMAB-01115) at 1:200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining. |
| Application | WB,IHC-P,IHC-Fr,IF |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:400-800; IHC-Fr: 1:400-800; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. |
| Construction | Hybridoma Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. Monomer or homodimer; in equilibrium. Binds to CCR2 and CCR4. Is tethered on endothelial cells by glycosaminoglycan (GAG) side chains of proteoglycans. Processing at the N-terminus can regulate receptor and targetcell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant. Genetic variations in CCL2 determine Mycobacterium tuberculosis susceptibility Belongs to the intercrine beta (chemokine CC) family. The MCP-1( the monocyte chemotactic protein1) has many pits that regulates the function toward sex to turn to record the factor, it can induce to have relation with inflammation with the immunity various genes turn to record.The immunity MCP-1 set turns the male signal to mainly locate the afterbirth syrup inside. |
| Immunogen | KLH conjugated synthetic peptide: rat MCP-1 |
| Antigen Species | Rat |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Response to hypoxia,Chemokines,Alpha Chemokines (CXC),Hypoxia,Heart disease |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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