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Anti-VAPB Antibody (7N811) is a Rabbit antibody targeting VAPB. Anti-VAPB Antibody (7N811) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $270 | 7-10 days |
Description | Anti-VAPB Antibody (7N811) is a Rabbit antibody targeting VAPB. Anti-VAPB Antibody (7N811) can be used in ELISA. |
Alias | VAP-B, VAMP-B, VAMP (vesicle-associated membrane protein)-associated protein B and C, ALS8 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 7N811 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 1:5000-1:10000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human VAPB / VAP-B (rh VAPB / VAP-B; TMPY-02196; O95292-1; Met 1-Pro 132). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Vesicle-associated membrane protein-associated protein B / C, also known as VAMP-B/VAMP-C, VAMP-associated protein B/C, VAP-B/VAP-C and VAPB, is a single-pass type IV membrane protein that belongs to the VAMP-associated protein (VAP) family. VAPB contains one MSP domain. VAPB may play a role in vesicle trafficking. VAPB forms a heterodimer with VAPA. VAPB interacts with VAMP1 and VAMP2. Defects in VAPB are the cause of amyotrophic lateral sclerosis type 8 ( ALS8 ) which is a familial form of amyotrophic lateral sclerosis, a neurodegenerative disorder affecting upper and lower motor neurons and resulting in fatal paralysis. Defects in VAPB are also a cause of spinal muscular atrophy autosomal dominant Finkel type (SMAF) which is characterized by proximal muscle weakness that begins in the lower limbs and then progresses to upper limbs. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human VAPB / VAP-B protein (TMPY-02196) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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