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Anti-APC6 Antibody (1Q510)
😃Good
Catalog No. TMAC-00240
Alias Cyclosome subunit 6, CUT9, Cell division cycle protein 16 homolog, Cell division cycle 16 homolog, Cell division cycle 16, CDC16Hs, CDC16_HUMAN, CDC16 protein, CDC16 homolog, CDC16 (cell division cycle 16 S. cerevisiae homolog), Cdc16, CDC 16, Apc 6, Anaphase-promoting complex subunit 6, Anaphase promoting complex subunit 6, ANAPC6
Anti-APC6 Antibody (1Q510) is a Rabbit antibody targeting APC6. Anti-APC6 Antibody (1Q510) can be used in WB,ICC/IF.
Anti-APC6 Antibody (1Q510)
Anti-APC6 Antibody (1Q510)
😃Good
Catalog No. TMAC-00240Alias Cyclosome subunit 6, CUT9, Cell division cycle protein 16 homolog, Cell division cycle 16 homolog, Cell division cycle 16, CDC16Hs, CDC16_HUMAN, CDC16 protein, CDC16 homolog, CDC16 (cell division cycle 16 S. cerevisiae homolog), Cdc16, CDC 16, Apc 6, Anaphase-promoting complex subunit 6, Anaphase promoting complex subunit 6, ANAPC6
Anti-APC6 Antibody (1Q510) is a Rabbit antibody targeting APC6. Anti-APC6 Antibody (1Q510) can be used in WB,ICC/IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $497 | 7-10 days |
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Chemical Properties
| Description | Anti-APC6 Antibody (1Q510) is a Rabbit antibody targeting APC6. Anti-APC6 Antibody (1Q510) can be used in WB,ICC/IF. |
| Synonyms | Cyclosome subunit 6, CUT9, Cell division cycle protein 16 homolog, Cell division cycle 16 homolog, Cell division cycle 16, CDC16Hs, CDC16_HUMAN, CDC16 protein, CDC16 homolog, CDC16 (cell division cycle 16 S. cerevisiae homolog), Cdc16, CDC 16, Apc 6, Anaphase-promoting complex subunit 6, Anaphase promoting complex subunit 6, ANAPC6 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of APC6 on Hela cells lysates using anti-APC6 antibody at 1/1,000 dilution. 2. ICC staining APC6 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining APC6 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. ICC staining APC6 in RH-35 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| Application | |
| Recommended Dose | WB: 1:1000-2000; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Cell cycle events are regulated by the sequential activation and deactivation of cyclin dependent kinases (Cdks) and by the proteolysis of cyclins. The cell division cycle (Cdc) genes are required at various points in the cell cycle. Cdc25A, Cdc25B and Cdc25C protein tyrosine phosphatases function as mitotic activators by dephosphorylating Cdc2 p34 on regulatory tyrosine residues. Cdc6 is the human homolog of Saccharomyces cerevisiae Cdc6, which is involved in the initiation of DNA replication. Cdc37 appears to facilitate Cdk4/cyclin D1 complex formation and has been shown to form a stable complex with Hsp90. Cdc34, Cdc27 and Cdc16 function as ubiquitin-conjugating enzymes. Cdc34 is thought to be the structural and functional homolog of Saccharomyces cerevisiae Cdc34, which is essential for the G1 to S phase transition. Cdc16 and Cdc27 are components of the APC (anaphase-promoting complex) which ubiquitinates cyclin B, resulting in cyclin B/Cdk complex degradation. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 72 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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