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Coagulation factor XI Protein, Cynomolgus, Recombinant (His)
(Synonyms: PTA, FXI, F11, Coagulation factor XI) Copy Product InfoSynonyms: PTA, FXI, F11, Coagulation factor XI
Catalog No. TMPK-01271 Copy Product Info
Factor XI (FXI) is the zymogen of a plasma protease (FXIa) that contributes to hemostasis by activating factor IX (FIX). In the original cascade model of coagulation, FXI is converted to FXIa by factor XIIa (FXIIa), a component, along with prekallikrein and high-molecular-weight kininogen (HK), of the plasma kallikrein-kinin system (KKS).
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 µg | $92 | 7-10 days | 7-10 days | |
| 20 µg | $148 | 7-10 days | 7-10 days | |
| 50 µg | $289 | 7-10 days | 7-10 days | |
| 100 µg | $487 | 7-10 days | 7-10 days | |
| 200 µg | $883 | 7-10 days | 7-10 days | |
| 500 µg | $1,950 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized Cynomolgus Coagulation factor XI, His Tag at 0.5 μg/mL (100 μL/well) on the plate. Dose response curve for Anti-Factor XI Antibody, hFc Tag with the EC50 of 4.9 ng/mL determined by ELISA (QC Test). |
| Description | Factor XI (FXI) is the zymogen of a plasma protease (FXIa) that contributes to hemostasis by activating factor IX (FIX). In the original cascade model of coagulation, FXI is converted to FXIa by factor XIIa (FXIIa), a component, along with prekallikrein and high-molecular-weight kininogen (HK), of the plasma kallikrein-kinin system (KKS). |
| Species | Cynomolgus |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | XP_005556540.2 |
| Construction | Glu44-Ala650 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Supplied as 0.22 μm filtered solution in PBS (pH 7.4). |
| Synonyms | PTA, FXI, F11, Coagulation factor XI |
| Research Background | Factor XI (FXI) is the zymogen of a plasma protease (FXIa) that contributes to hemostasis by activating factor IX (FIX). In the original cascade model of coagulation, FXI is converted to FXIa by factor XIIa (FXIIa), a component, along with prekallikrein and high-molecular-weight kininogen (HK), of the plasma kallikrein-kinin system (KKS). |
| Molecular Weight | 69.05 kDa (predicted). Due to glycosylation, the protein migrates to 70-85 kDa based on Tris-Bis PAGE result. |
| Shipping | Proteins are shipped with blue ice. |
| Storage | It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: Coagulation factor XI Protein, Cynomolgus, Recombinant (His) chemical structure | Coagulation factor XI Protein, Cynomolgus, Recombinant (His) molecular weight
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