OGG1 Protein, Human, Recombinant

Name: OGG1 Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPJ-00457
Rating: 4.5 (1 reviews)

(Synonyms: OGH1, OGG1, N-Glycosylase/DNA Lyase, MUTM, MMH, DNA-(Apurinic or Apyrimidinic Site) Lyase, AP Lyase, 8-Oxoguanine DNA Glycosylase) Copy Product Info

Synonyms: OGH1, OGG1, N-Glycosylase/DNA Lyase, MUTM, MMH, DNA-(Apurinic or Apyrimidinic Site) Lyase, AP Lyase, 8-Oxoguanine DNA Glycosylase

Catalog No. TMPJ-00457 Copy Product Info

Human N-Glycosylase/DNA Lyase(OOG1) is a DNA repair enzyme, which belongs to the type-1 OGG1 family. OOG1 incises DNA at 8-oxoG residues, and excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damage DNA. It has a β-lyase activity that nicks DNA 3' to the lesion. OOG1 together with APEX1 is recruited to nuclear speckles in UVA-irradiated cells. The OGG1 gene mutations may be caused Renal cell carcinoma.

Pack Size	Price	USA Stock	Global Stock
5 μg	$80	7-10 days	7-10 days
10 μg	$129	7-10 days	7-10 days
20 μg	$198	7-10 days	7-10 days
50 μg	$390	7-10 days	7-10 days
100 μg	$626	7-10 days	7-10 days
200 μg	$987	7-10 days	7-10 days
500 μg	$1,900	7-10 days	7-10 days
1 mg	$2,730	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Human N-Glycosylase/DNA Lyase(OOG1) is a DNA repair enzyme, which belongs to the type-1 OGG1 family. OOG1 incises DNA at 8-oxoG residues, and excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damage DNA. It has a β-lyase activity that nicks DNA 3' to the lesion. OOG1 together with APEX1 is recruited to nuclear speckles in UVA-irradiated cells. The OGG1 gene mutations may be caused Renal cell carcinoma.
Species	Human
Expression System	E. coli
Tag	N-GST
Accession Number	AAH00657.1
Amino Acid	Met1-Gly345
Construction	Met1-Gly345
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 1 mM EDTA, pH 8.5.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Proteins are shipped with blue ice.
Synonyms	OGH1, OGG1, N-Glycosylase/DNA Lyase, MUTM, MMH, DNA-(Apurinic or Apyrimidinic Site) Lyase, AP Lyase, 8-Oxoguanine DNA Glycosylase
Research Background

Chemical Properties

Molecular Weight

38 KDa (reducing condition)

Storage & Solubility Information

Storage

Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

OGH-1OGH 1OGG-1OGG 1

Related Tags: OGG1 Protein, Human, Recombinant chemical structure | OGG1 Protein, Human, Recombinant molecular weight