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(R)-Amlodipine

🥰Excellent
Catalog No. T21265Cas No. 103129-81-3
Alias D-Amlodipine, (+)-Amlodipine

(R)-Amlodipine is the R-enantiomer of Amlodipine and functions as an orally active dihydropyridine calcium channel blocker with antianginal properties, (R)-Amlodipine excerts its effect by blocking voltage-dependent L-type calcium channels and thus reducing calcium influx into cells. (R)-Amlodipine can be employed in research concerning high blood pressure and cancer, as (R)-Amlodipine calcium channel regulation ability provide a mechanistic basis for investigating cardiovascular disorders and tumor-related pathophysiology.

(R)-Amlodipine
Other Forms of (R)-Amlodipine:

(R)-Amlodipine

🥰Excellent
Purity: 99.977%
Catalog No. T21265Alias D-Amlodipine, (+)-AmlodipineCas No. 103129-81-3
(R)-Amlodipine is the R-enantiomer of Amlodipine and functions as an orally active dihydropyridine calcium channel blocker with antianginal properties, (R)-Amlodipine excerts its effect by blocking voltage-dependent L-type calcium channels and thus reducing calcium influx into cells. (R)-Amlodipine can be employed in research concerning high blood pressure and cancer, as (R)-Amlodipine calcium channel regulation ability provide a mechanistic basis for investigating cardiovascular disorders and tumor-related pathophysiology.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$35-In Stock
10 mg$56-In Stock
25 mg$113-In Stock
50 mg$168-In Stock
100 mg$248-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.977%
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Product Introduction

Bioactivity
Description
(R)-Amlodipine is the R-enantiomer of Amlodipine and functions as an orally active dihydropyridine calcium channel blocker with antianginal properties, (R)-Amlodipine excerts its effect by blocking voltage-dependent L-type calcium channels and thus reducing calcium influx into cells. (R)-Amlodipine can be employed in research concerning high blood pressure and cancer, as (R)-Amlodipine calcium channel regulation ability provide a mechanistic basis for investigating cardiovascular disorders and tumor-related pathophysiology.
SynonymsD-Amlodipine, (+)-Amlodipine
Chemical Properties
Molecular Weight408.88
FormulaC20H25ClN2O5
Cas No.103129-81-3
SmilesC(OCC)(=O)C=1[C@@H](C(C(OC)=O)=C(C)NC1COCCN)C2=C(Cl)C=CC=C2
Relative Density.1.228g/cm3
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagestore at low temperature,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (195.66 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween-80+45% Saline: 3.3 mg/mL (8.07 mM), Sonication is recommeded.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4457 mL12.2285 mL24.4571 mL122.2853 mL
5 mM0.4891 mL2.4457 mL4.8914 mL24.4571 mL
10 mM0.2446 mL1.2229 mL2.4457 mL12.2285 mL
20 mM0.1223 mL0.6114 mL1.2229 mL6.1143 mL
50 mM0.0489 mL0.2446 mL0.4891 mL2.4457 mL
100 mM0.0245 mL0.1223 mL0.2446 mL1.2229 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Keywords

Amlodipine(R)Amlodipine(R)-(+)-Amlodipine(R) Amlodipine
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