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(R)-Amlodipine

🥰Excellent
Catalog No. T21265Cas No. 103129-81-3
Alias D-Amlodipine, (+)-Amlodipine

(R)-Amlodipine is the R-enantiomer of Amlodipine and functions as an orally active dihydropyridine calcium channel blocker with antianginal properties, (R)-Amlodipine excerts its effect by blocking voltage-dependent L-type calcium channels and thus reducing calcium influx into cells. (R)-Amlodipine can be employed in research concerning high blood pressure and cancer, as (R)-Amlodipine calcium channel regulation ability provide a mechanistic basis for investigating cardiovascular disorders and tumor-related pathophysiology.

(R)-Amlodipine
Other Forms of (R)-Amlodipine:

(R)-Amlodipine

🥰Excellent
Purity: 99.977%
Catalog No. T21265Alias D-Amlodipine, (+)-AmlodipineCas No. 103129-81-3
(R)-Amlodipine is the R-enantiomer of Amlodipine and functions as an orally active dihydropyridine calcium channel blocker with antianginal properties, (R)-Amlodipine excerts its effect by blocking voltage-dependent L-type calcium channels and thus reducing calcium influx into cells. (R)-Amlodipine can be employed in research concerning high blood pressure and cancer, as (R)-Amlodipine calcium channel regulation ability provide a mechanistic basis for investigating cardiovascular disorders and tumor-related pathophysiology.
Pack SizePriceAvailabilityQuantity
5 mg$35In Stock
10 mg$56In Stock
25 mg$113In Stock
50 mg$168In Stock
100 mg$248In Stock
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Purity:99.977%
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Product Introduction

Bioactivity
Description
(R)-Amlodipine is the R-enantiomer of Amlodipine and functions as an orally active dihydropyridine calcium channel blocker with antianginal properties, (R)-Amlodipine excerts its effect by blocking voltage-dependent L-type calcium channels and thus reducing calcium influx into cells. (R)-Amlodipine can be employed in research concerning high blood pressure and cancer, as (R)-Amlodipine calcium channel regulation ability provide a mechanistic basis for investigating cardiovascular disorders and tumor-related pathophysiology.
SynonymsD-Amlodipine, (+)-Amlodipine
Chemical Properties
Molecular Weight408.88
FormulaC20H25ClN2O5
Cas No.103129-81-3
SmilesC(OCC)(=O)C=1[C@@H](C(C(OC)=O)=C(C)NC1COCCN)C2=C(Cl)C=CC=C2
Relative Density.1.228g/cm3
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagestore at low temperature,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (195.66 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4457 mL12.2285 mL24.4571 mL122.2853 mL
5 mM0.4891 mL2.4457 mL4.8914 mL24.4571 mL
10 mM0.2446 mL1.2229 mL2.4457 mL12.2285 mL
20 mM0.1223 mL0.6114 mL1.2229 mL6.1143 mL
50 mM0.0489 mL0.2446 mL0.4891 mL2.4457 mL
100 mM0.0245 mL0.1223 mL0.2446 mL1.2229 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

Amlodipine(R)Amlodipine(R)-(+)-Amlodipine(R) Amlodipine
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