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Anti-TREM-2 Polyclonal Antibody
(Synonyms: triggering receptor expressed on myeloid cells 2, Trem2c, Trem2b, Trem2a, TREM-2) Copy Product Info
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Synonyms: triggering receptor expressed on myeloid cells 2, Trem2c, Trem2b, Trem2a, TREM-2
Catalog No. TMAB-01893 Copy Product Info
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Anti-TREM-2 Polyclonal Antibody is a Rabbit antibody targeting TREM-2. Anti-TREM-2 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.
Anti-TREM-2 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-TREM-2 Polyclonal Antibody is a Rabbit antibody targeting TREM-2. Anti-TREM-2 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB. |
| Synonyms | triggering receptor expressed on myeloid cells 2, Trem2c, Trem2b, Trem2a, TREM-2 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Isoform 1: Cell membrane; Single-pass type I membrane protein (Potential). Isoform 2: Secreted (Potential).Isoform 3: Secreted (Potential). |
| Tissue Specificity | Expressed on macrophages and dendritic cells but not on granulocytes or monocytes. In the CNS strongest expression seen in the basal ganglia, corpus callosum, medulla oblongata and spinal cord. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012] |
| Immunogen | KLH conjugated synthetic peptide: human TREM2 |
| Antigen Species | Human |
| Gene Name | TREM2 |
| Gene ID | |
| Protein Name | Triggering receptor expressed on myeloid cells 2 |
| Uniprot ID | |
| Biology Area | Macrophage / Inflamm. |
| Function | May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells. |
| Molecular Weight | Theoretical: 25 kDa. Actual: 24 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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