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Anti-CD27/TNFRSF7 Antibody-APC (4I709)

🥰Excellent
Catalog No. TMAY-03108A

Anti-CD27/TNFRSF7 Antibody-APC (4I709) is a APC-conjugated Rabbit antibody targeting CD27/TNFRSF7. Anti-CD27/TNFRSF7 Antibody-APC (4I709) can be used in FCM.

Anti-CD27/TNFRSF7 Antibody-APC (4I709)

Anti-CD27/TNFRSF7 Antibody-APC (4I709)

🥰Excellent
Catalog No. TMAY-03108A
Anti-CD27/TNFRSF7 Antibody-APC (4I709) is a APC-conjugated Rabbit antibody targeting CD27/TNFRSF7. Anti-CD27/TNFRSF7 Antibody-APC (4I709) can be used in FCM.
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Product Introduction

Bioactivity
Description
Anti-CD27/TNFRSF7 Antibody-APC (4I709) is a APC-conjugated Rabbit antibody targeting CD27/TNFRSF7. Anti-CD27/TNFRSF7 Antibody-APC (4I709) can be used in FCM.
Ig Type
Monoclonal Rabbit IgG
Clone
4I709
Reactivity
Mouse
Verified Activity
Expression of CD27 on mouse splenocytes. BABL/c splenocytes were stained with Anti-CD27 Antibody-APC.
Application
FCM
Recommended Dose
1 μl/Test, 0.1 mg/ml
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD27 (rM CD27; TMPY-01432; NP_001028298.1; Met1-Arg182) and conjugated with APC under optimum conditions, the unreacted APC was removed.
PurificationProtein A
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.09% sodium azide
Research BackgroundCD27, also known as TNFRSF7, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a type I transmembrane glycoprotein of about 55 kDa existing as disulfide-linked homodimer, CD27 has been shown to play roles in lymphoid proliferation, differentiation, and apoptosis.It has an important role in the generation of T cell immunity and is an robust marker for normal memory B cells. It is a T and B cell co-stimulatory molecule, the activity of CD27 is governed by its TNF-like ligand CD70 on lymphocytes and dendritic cells. The CD27-CD70 interaction is required for Th1 generation responses to differentiation signals and long-term maintenance of T cell immunity, and meanwhile, plays a key role in regulating B-cell differentiation, activation and immunoglobulin synthesis.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
APC
Others Formats
Unconjugated/PerCP/FITC/PE
Antibody Types Available
5
Antigen Details
Immunogen
Recombinant Mouse CD27 protein (TMPY-01432)
Antigen Species
Mouse
Biology Area
Cancer Drug Targets
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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