4-1BB Ligand/TNFSF9 Protein, Mouse, Recombinant (His)

Name: 4-1BB Ligand/TNFSF9 Protein, Mouse, Recombinant (His)
Brand: TargetMol
SKU: TMPY-00959
Rating: 4.5 (1 reviews)

(Synonyms: tumor necrosis factor (ligand) superfamily, member 9, Ly63l, Cd137l, AI848817, 4-1BB-L, 4-1BBL) Copy Product Info

Synonyms: tumor necrosis factor (ligand) superfamily, member 9, Ly63l, Cd137l, AI848817, 4-1BB-L, 4-1BBL

Catalog No. TMPY-00959 Copy Product Info

4-1BB Ligand/TNFSF9 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is P41274.

Pack Size	Price	USA Stock	Global Stock
5 µg	$73	7-10 days	7-10 days
10 µg	$118	7-10 days	7-10 days
20 µg	$196	7-10 days	7-10 days
50 µg	$383	7-10 days	7-10 days
100 µg	$673	7-10 days	7-10 days
200 µg	$1,180	7-10 days	7-10 days
500 µg	$2,880	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Resource Download

User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Measured by its binding ability in a functional ELISA. Immobilized recombinant mouse 4-1BB Ligand at 20 μg/ml (100ul/well) can bind human 4-1BB with a linear range of 15.6-500 ng/ml.
Description	4-1BB Ligand/TNFSF9 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is P41274.
Species	Mouse
Expression System	HEK293 Cells
Tag	N-His
Accession Number	P41274
Construction	A DNA sequence encoding the extracellular domain (Arg 104-Glu 309) of mouse TNFSF9 (NP_033430.1) precursor was expressed with a N-terminal polyhistidine tag. Predicted N terminal: His
Protein Purity	> 97 % as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonyms	tumor necrosis factor (ligand) superfamily, member 9, Ly63l, Cd137l, AI848817, 4-1BB-L, 4-1BBL
Research Background	4-1BB ligand is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. It is shown to be a type II surface glycoprotein belonging to the TNF superfamily. Expression of 4-1BBL is restricted to APCs, such as dendritic cells, macrophages, and activated B cells. Members of the TNF-TNF receptor superfamily have been shown to play critical roles in regulating cellular activation, differentiation and apoptosis. Several studies have reported that 4-1BBL/4-1BB interaction provided a co-stimulatory signal to T cells, and increased T cell proliferation and cytokines production. In addition, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy

Chemical Properties

Molecular Weight

25 kDa (predicted); 40-45 kDa (reducing condition, due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Calculator

Reconstitution Calculator
Recombinant Protein Dilution Calculator
Specific Activity Calculator

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Recombinant Proteins

Keywords

AI-848817AI 848817

Related Tags: 4-1BB Ligand/TNFSF9 Protein, Mouse, Recombinant (His) chemical structure | 4-1BB Ligand/TNFSF9 Protein, Mouse, Recombinant (His) molecular weight