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Anti-S100P Antibody (1S30)
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Catalog No. TMAY-02402
Alias S100 calcium binding protein P, MIG9
Anti-S100P Antibody (1S30) is a Rabbit antibody targeting S100P. Anti-S100P Antibody (1S30) can be used in IHC-P,ICC/IF.
Anti-S100P Antibody (1S30)
Anti-S100P Antibody (1S30)
😃Good
Catalog No. TMAY-02402Alias S100 calcium binding protein P, MIG9
Anti-S100P Antibody (1S30) is a Rabbit antibody targeting S100P. Anti-S100P Antibody (1S30) can be used in IHC-P,ICC/IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $270 | 7-10 days |
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| Description | Anti-S100P Antibody (1S30) is a Rabbit antibody targeting S100P. Anti-S100P Antibody (1S30) can be used in IHC-P,ICC/IF. |
| Alias | S100 calcium binding protein P, MIG9 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 1S30 |
| Reactivity | Human |
| Verified Activity | 1. Immunochemical staining of human S100P in human spleen with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human S100P in human placenta with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). The image showing nucleus staining of trophoblastic cells. 3. Immunofluorescence staining of S100P in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS,blocked with 10% serum, and incubated with rabbit anti-Y S100P monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor®594-conjugated Goat Anti-rabbit IgG secondary antibody (red). Positive staining was localized to Nucleus and Cytoplasm. |
| Application | IHC-P,ICC/IF |
| Recommended Dose | IHC-P: 1:100-1:500; ICC-IF: 1:20-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human S100P (rh S100P; TMPY-02216; P25815; Met1-Lys95). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Protein S100-P, also known as Protein S100-E, S100 calcium-binding protein P, S100P and S100E, is a nucleus and cytoplasm protein that belongs to the S-100 family. S100P / S100E contains twoEF-hand domains. S100P protein regulates calcium signal transduction and mediates cytoskeletal interaction, protein phosphorylation and transcriptional control. S100P / S100E overexpression can upregulate androgen receptor expression and thereby promote prostate cancer progression by increasing cell growth. S100P / S100E may directly confer resistance to chemotherapy. S100P / S100E induction may be considered an important step in the initial stage of lung adenocarcinomas, whereas its downregulation in advanced stages seems to be important for tumour progression in which DNA methylation and/or feedback transcription processes play a critical role. S100P / S100E plays a major role in the aggressiveness of pancreatic cancer that is likely mediated by its ability to activate RAGE. Interference with S100P / S100E may provide a novel approach for treatment of pancreatic cancer. S100P / S100E could be considered a potential drug target or a chemosensitization target, and could also serve as a biomarker for aggressive, hormone-refractory and metastatic prostate cancer. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human S100P protein (TMPY-02216) |
| Antigen Species | Human |
| Biology Area | Calcium-binding Proteins and Related Molecules |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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