Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(R)-Omeprazole is the inactive isomer of omeprazole , a gastric proton-pump inhibitor. A stereoselective hydroxylation of (R)-omeprazole is mediated primarily by cytochrome P450 (CYP) 2C19, whereas CYP3A4 favors sulfoxidation of the active (S)-enantiomer . (R)-Omeprazole has been shown to act as a reversible direct-acting and metabolism-dependent inhibitor of CYP2C19 in pooled human liver microsomes (IC50 = 8.1 μM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 μg | 35 days | $ 198.00 | |
1 mg | 35 days | $ 343.00 | |
5 mg | 35 days | $ 1,510.00 |
Description | (R)-Omeprazole is the inactive isomer of omeprazole , a gastric proton-pump inhibitor. A stereoselective hydroxylation of (R)-omeprazole is mediated primarily by cytochrome P450 (CYP) 2C19, whereas CYP3A4 favors sulfoxidation of the active (S)-enantiomer . (R)-Omeprazole has been shown to act as a reversible direct-acting and metabolism-dependent inhibitor of CYP2C19 in pooled human liver microsomes (IC50 = 8.1 μM). |
Molecular Weight | 368.41 |
Formula | C17H19N3NaO3S |
CAS No. | 161796-77-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 1 mg/mL
DMSO: 5 mg/mL
PBS (pH 7.2): 5 mg/mL
DMF: 5 mg/mL
You can also refer to dose conversion for different animals. More
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(R)-Omeprazole (sodium salt) 161796-77-6 (R) Omeprazole (sodium salt) (R)Omeprazole (sodium salt) Omeprazole inhibitor inhibit