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Landipirdine

Name: Landipirdine
Brand: TargetMol
SKU: T27795
Price: 247 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T27795Cas No. 1000308-25-7

Alias SYN-120, SYN120, SYN 120, RO-5025181, RO5025181, RO 5025181

Landipirdine (RO-5025181) is a selective 5-HT6R antagonist for the study of central nervous system disorders such as dementia.

Landipirdine

🥰Excellent

Purity: 99.37%

Catalog No. T27795Alias SYN-120, SYN120, SYN 120, RO-5025181, RO5025181, RO 5025181Cas No. 1000308-25-7

Landipirdine (RO-5025181) is a selective 5-HT6R antagonist for the study of central nervous system disorders such as dementia.

Pack Size	Price	Availability
1 mg	$247	In Stock
5 mg	$591	In Stock
10 mg	$793	In Stock
25 mg	$1,280	In Stock
50 mg	$1,630	In Stock
100 mg	$2,320	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.37%

ee:100%

Resource Download

COA CSFC FNMR HNMR LCMS

Product Introduction

Bioactivity

Description	Landipirdine (RO-5025181) is a selective 5-HT6R antagonist for the study of central nervous system disorders such as dementia.
Synonyms	SYN-120, SYN120, SYN 120, RO-5025181, RO5025181, RO 5025181

Chemical Properties

Molecular Weight	362.42
Formula	C₁₈H₁₉FN₂O₃S
Cas No.	1000308-25-7
Smiles	C(NC(N)=O)[C@H]1C=2C(=CC(S(=O)(=O)C3=CC(F)=CC=C3)=CC2)CCC1
Relative Density.	1.313 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (124.17 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7592 mL	13.7961 mL	27.5923 mL	137.9615 mL
5 mM	0.5518 mL	2.7592 mL	5.5185 mL	27.5923 mL
10 mM	0.2759 mL	1.3796 mL	2.7592 mL	13.7961 mL
20 mM	0.1380 mL	0.6898 mL	1.3796 mL	6.8981 mL
50 mM	0.0552 mL	0.2759 mL	0.5518 mL	2.7592 mL
100 mM	0.0276 mL	0.1380 mL	0.2759 mL	1.3796 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc