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Coproporphyrin III dihydrochloride, a bioactive compound secreted by nostril- and skin-associated Propionibacterium species, promotes the aggregation of Staphylococcus aureus during early stationary phase growth at a low pH of 4-6. In addition, it facilitates plasma-independent biofilm formation by S. aureus on non-living surfaces. This compound could play a crucial role in mediating the accumulation and biofilm development of S. aureus in nasal passages or other locations where both Propionibacterium and S. aureus coexist.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks | 10-14 weeks |
| Description | Coproporphyrin III dihydrochloride, a bioactive compound secreted by nostril- and skin-associated Propionibacterium species, promotes the aggregation of Staphylococcus aureus during early stationary phase growth at a low pH of 4-6. In addition, it facilitates plasma-independent biofilm formation by S. aureus on non-living surfaces. This compound could play a crucial role in mediating the accumulation and biofilm development of S. aureus in nasal passages or other locations where both Propionibacterium and S. aureus coexist. |
| Synonyms | Zincphyrin dihydrochloride |
| Molecular Weight | 727.63 |
| Formula | C36H40Cl2N4O8 |
| Cas No. | 68938-73-8 |
| Smiles | O=C(CCC1=C(C)C2=NC1=CC3=C(C)C(CCC(O)=O)=C(N3)C=C(C(CCC(O)=O)=C4C)N=C4C=C(C(C)=C5CCC(O)=O)NC5=C2)O.Cl.Cl |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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