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TFPI Protein, Human, Recombinant (His & Avi)

Catalog No. TMPK-00194
Synonyms: LACI, EPI, TFPI, convertin, TFI, TFPI1

Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and has recently been associated with breast cancer cell development.

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TFPI Protein, Human, Recombinant (His & Avi)
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 442.00
500 μg 5 days $ 1,760.00
1 mg 5 days $ 2,950.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and has recently been associated with breast cancer cell development.
Species Human
Expression System HEK293
Tag C-His-Avi
Accession Number P10646-1
Synonyms LACI, EPI, TFPI, convertin, TFI, TFPI1
Construction Recombinant Human TFPI Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. It contains Asp29-Lys282.[Accession |P10646-1]
Protein Purity > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight The protein has a predicted MW of 32.1 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
Endotoxin Less than 1EU per μg by the LAL method.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability & Storage

-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and has recently been associated with breast cancer cell development.

References and Literature

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Keywords

TFPI Protein, Human, Recombinant (His & Avi) LACI TFPI 1 TFPI-1 EPI TFPI convertin TFI TFPI1 recombinant recombinant-proteins proteins protein

 

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