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Anti-IFNGR1 Antibody-PE (4Q133) is a PE-conjugated Rabbit antibody targeting IFNGR1. Anti-IFNGR1 Antibody-PE (4Q133) can be used in FCM.
Description | Anti-IFNGR1 Antibody-PE (4Q133) is a PE-conjugated Rabbit antibody targeting IFNGR1. Anti-IFNGR1 Antibody-PE (4Q133) can be used in FCM. |
Ig Type | Monoclonal Rabbit IgG |
Clone | 4Q133 |
Reactivity | Mouse |
Verified Activity | Flow cytometric analysis of Mouse IFNGR1 (CD119) expression on mouse splenocytes. BABL/c splenocytes were stained with PE-conjugated anti-Mouse IFNGR1 (CD119). The histogram were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
Application | FCM |
Recommended Dose | 10 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IFNGR1 / CD119 (rM IFNGR1 / CD119; TMPY-02355; P15261; Met1-Asp253) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
Purification | Protein A |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
Research Background | The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alters the behavior of the cell. Some CD proteins do not take part in the cell signal process but have other functions such as cell adhesion. CD119 (cluster of differentiation 119), also known as IFNGR1 ( interferon-gamma receptor 1), is part of the heterodimeric gamma interferon receptor which consists of IFNGR1 (CD119) and IFNGR2. The IFNGR1 gene encodes the ligand-binding chain (alpha) of the interferon receptor while the IFNGR gene encodes the non-ligand binding partner. The ability of the interferon-γ was achieved through binding to the interferon receptor CD119. After binding, the products of activated T-lymphocytes interferon-γ exerts antiviral activity, growth inhibitory effect, and several immune- regulatory activities on a variety of cell types. |
Conjucates | PE |
Others Formats | Unconjugated/APC/FITC |
Antibody Types Available | 4 |
Immunogen | Recombinant Mouse IFNGR1 / CD119 protein (TMPY-02355) |
Antigen Species | Mouse |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
Transport | Shipping with blue ice. |
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