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Anti-CCL19/MIP-3b Polyclonal Antibody is a Rabbit antibody targeting CCL19/MIP-3b. Anti-CCL19/MIP-3b Polyclonal Antibody can be used in ELISA,IF,IHC-Fr,IHC-P,WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $222 | 7-10 days | |
100 μL | $373 | 7-10 days | |
200 μL | $529 | 7-10 days |
Description | Anti-CCL19/MIP-3b Polyclonal Antibody is a Rabbit antibody targeting CCL19/MIP-3b. Anti-CCL19/MIP-3b Polyclonal Antibody can be used in ELISA,IF,IHC-Fr,IHC-P,WB. |
Synonyms | Small-inducible cytokine A19, Scya19, Epstein-Barr virus-induced molecule 1 ligand chemokine (EBI1 ligand chemokine;ELC), ELC, Ccl19, C-C motif chemokine 19 |
Ig Type | IgG |
Reactivity | (predicted:Human,Mouse,Rat,Pig) |
Application | |
Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Secreted. |
Tissue Specificity | Highly expressed by dendritic cells in mesenteric and peripheral lymph nodes. Significant expression in spleen (T cell zone or periarteriolar lymphatic sheath) and Peyer patches. Low expression in thymus. |
Construction | Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Concentration | 1 mg/mL |
Research Background | This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene may play a role in normal lymphocyte recirculation and homing. It also plays an important role in trafficking of T cells in thymus, and in T cell and B cell migration to secondary lymphoid organs. It specifically binds to chemokine receptor CCR7. [provided by RefSeq, Jul 2008] |
Immunogen | KLH conjugated synthetic peptide: mouse CCL19 |
Antigen Species | Mouse |
Gene Name | CCL19 |
Gene ID | |
Protein Name | C-C motif chemokine 19 |
Uniprot ID | |
Biology Area | Beta Chemokines (CC),Macrophage / Inflamm.,Cytokines and cytokine receptors ELISA kits,GPCR |
Function | Strongly chemotactic for naive (L-selectinhi) CD4 T-cells and for CD8 T-cells and weakly attractive for resting B-cells and memory (L-selectinlo) CD4 T-cells. May play a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues. Specifically binds to chemokine receptor CCR7. |
Molecular Weight | Theoretical: 9.2 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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