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CD19 Protein, Cynomolgus/Rhesus, Recombinant (His), Biotinylated

(Synonyms: CD19 molecule) Copy Product Info

Synonyms: CD19 molecule

Catalog No. TMPY-05530 Copy Product Info
CD19 Protein, Cynomolgus/Rhesus, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.4 kDa and the accession number is XP_005591597.1.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$917-10 days7-10 days
10 µg$1487-10 days7-10 days
20 µg$245-In Stock
50 µg$3937-10 days7-10 days
100 µg$5897-10 days7-10 days
200 µg$1,0007-10 days7-10 days
500 µg$2,0307-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:93.6%
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Bioactivity
Immobilized CD19 Antibody, Rabbit PAb, Antigen Affinity Purified at 2 μg/mL (100 μL/well) can bind Recombinant Cynomolgus/Rhesus CD19 Protein (His Tag), Biotinylated(Cat#TMPY-05530), the EC50 is 60-180 ng/mL.
Description
CD19 Protein, Cynomolgus/Rhesus, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.4 kDa and the accession number is XP_005591597.1.
Species
Cynomolgus,Rhesus
Expression System
HEK293 Cells
TagC-His
Accession NumberXP_005591597.1
ConstructionA DNA sequence encoding the cynomolgus / rhesus CD19 ( XP_005591597.1) (Met1-Lys292) was expressed with a polyhistidine tag at the C-terminus. Cynomolgus and Rhesus CD19 sequences are identical. The purified protein was biotinylated in vitro. Predicted N terminal: Gln 21
Protein Purity
> 90 % as determined by SDS-PAGE.
CD19 Protein, Cynomolgus/Rhesus, Recombinant (His), Biotinylated
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
ReconstitutionReconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
SynonymsCD19 molecule
Research Background
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 19 (CD19) is a member of CD system. CD19 is a cell surface molecule that assembles with the antigen receptor of B-cells. This results in a descent in the threshold for antigen receptor-dependent stimulation. A simplified view holds that the ability of B-cells to respond to the various antigens in a specific and sensitive manner is achieved in the presence of low-affinity antigen receptors. CD19 primarily acts as a B-cell co-receptor in conjunction with CD21 and CD81. The formation of the receptor complex is induced by antigen and CD19, induced by exogenous antigen, has been found cytoplasmic tail phosphorylated and bind to sIg.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Chemical Properties
Molecular Weight31.4 kDa (predicted)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: CD19 Protein, Cynomolgus/Rhesus, Recombinant (His), Biotinylated chemical structure | CD19 Protein, Cynomolgus/Rhesus, Recombinant (His), Biotinylated molecular weight