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Anti-Phospho-STAT2 (Tyr690) Polyclonal Antibody is a Rabbit antibody targeting Phospho-STAT2 (Tyr690). Anti-Phospho-STAT2 (Tyr690) Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $222 | 7-10 days | |
100 μL | $374 | 7-10 days | |
200 μL | $529 | 7-10 days |
Description | Anti-Phospho-STAT2 (Tyr690) Polyclonal Antibody is a Rabbit antibody targeting Phospho-STAT2 (Tyr690). Anti-Phospho-STAT2 (Tyr690) Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF. |
Alias | STAT2 (p-Y690), STAT2 (p-Tyr690), p-STAT2 (Y690), p-STAT2 (Tyr690) |
Ig Type | IgG |
Reactivity | Mouse (predicted:Human,Rat,Dog,Horse) |
Verified Activity | 1. Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (Stat2 (Tyr690)) Polyclonal Antibody, Unconjugated (TMAB-01506) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining. 2. Sample: Brain (Mouse) Lysate at 40 μg Primary: Anti-Phospho-Stat2 (Tyr690)(TMAB-01506) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 94 kDa Observed band size: 105 kDa |
Application | WB,IHC-P,IHC-Fr,IF |
Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Cytoplasm. Nucleus. Note=Translocated into the nucleus upon activation by IFN-alpha/beta. |
Construction | Hybridoma Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Research Background | The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]. |
Immunogen | KLH conjugated Synthesised phosphopeptide: human Stat2 around the phosphorylation site of Tyr690 |
Antigen Species | Human |
Gene ID | |
Uniprot ID | |
Biology Area | STATs,Other factors,SARS Coronavirus,STATs |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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