This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.
This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.
1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin
Catalog No. T83826 CAS
57653-85-7
Synonyms:
1,2,3,6,7,8-HxCDD, PCDD 67
1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin, a polychlorinated dibenzodioxin (PCDD), acts as an agonist for the aryl hydrocarbon receptor (AhR; EC50s = 5.4 and 9.3 nM at 4 and 8 h, respectively, in a reporter assay). It has been observed to reduce antibody production against sheep red blood cells in mice at doses of 0.5 and 2 µg/kg. This compound has been detected in animal feed and in the vicinity of municipal waste incinerators.
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1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin, CAS 57653-85-7
1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin, a polychlorinated dibenzodioxin (PCDD), acts as an agonist for the aryl hydrocarbon receptor (AhR; EC50s = 5.4 and 9.3 nM at 4 and 8 h, respectively, in a reporter assay). It has been observed to reduce antibody production against sheep red blood cells in mice at doses of 0.5 and 2 µg/kg. This compound has been detected in animal feed and in the vicinity of municipal waste incinerators.
Synonyms
1,2,3,6,7,8-HxCDD, PCDD 67
Molecular Weight
390.86
Formula
C12H2Cl6O2
CAS No.
57653-85-7
Storage
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
nonane:toluene (8:2): soluble
Dose Conversion
You can also refer to dose conversion for different animals.
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Method for preparing DMSO master liquid: mg
drug pre-dissolved in μL DMSO (Master liquid concentration
mg/mL),
Method for preparing in vivo formulation:Take μL
DMSO master liquid, next add μL PEG300, mix and clarify, next add μL
Tween 80,mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation:Take μL
DMSO master liquid, next add μL Corn oil,mix and clarify.
Note:
Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.