Interleukin-22 Receptor Subunit α-2 (IL22RA2) belongs to the type II cytokine receptor family. IL22RA2 is a secreted protein and contains three fibronectin type-III domains. IL22RA2 is widely expressed in many tissues. IL22RA2 functions as an IL22 antagonist and may be important in the regulation of inflammatory response. Three alternatively spliced transcript variants encoding distinct isoforms have been described.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 μg | 5 days | $ 129.00 | |
50 μg | 5 days | $ 390.00 | |
500 μg | 5 days | $ 1,900.00 | |
1 mg | 5 days | $ 2,730.00 |
Description | Interleukin-22 Receptor Subunit α-2 (IL22RA2) belongs to the type II cytokine receptor family. IL22RA2 is a secreted protein and contains three fibronectin type-III domains. IL22RA2 is widely expressed in many tissues. IL22RA2 functions as an IL22 antagonist and may be important in the regulation of inflammatory response. Three alternatively spliced transcript variants encoding distinct isoforms have been described. |
Species | Human |
Expression System | Human Cells |
Tag | C-Fc |
Accession Number | Q969J5-2 |
Synonyms | Cytokine Receptor Family 2 Member 10, CRF2-10, IL-22RA2, Interleukin-22 Receptor Subunit α-2, Interleukin-22-Bind, IL-22R-α-2, Interleukin-22 Receptor Subunit Alpha-2, IL-22 Receptor Subunit Alpha-2, Cytokine Receptor Family Type 2 Soluble 1, Cytokine Receptor Class-II Member 10, CRF2-S1, IL-22R-Alpha-2, IL-22 Receptor Subunit α-2 |
Amino Acid | Thr22-Pro231 |
Construction | Recombinant Human Interleukin-22 Receptor Subunit Alpha-2/Interleukin-22 Binding Protein is produced by our Mammalian expression system and the target gene encoding Thr22-Pro231 is expressed with a human IgG1 Fc tag at the C-terminus. |
Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
Molecular Weight | 80-100 KDa, reducing conditions |
Endotoxin | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Stability & Storage |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
Shipping |
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Research Background | Interleukin-22 Receptor Subunit α-2 (IL22RA2) belongs to the type II cytokine receptor family. IL22RA2 is a secreted protein and contains three fibronectin type-III domains. IL22RA2 is widely expressed in many tissues. IL22RA2 functions as an IL22 antagonist and may be important in the regulation of inflammatory response. Three alternatively spliced transcript variants encoding distinct isoforms have been described. |
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Please read the User Guide of Recombinant Proteins for more specific information.
IL-22RA2 Protein, Human, Recombinant (hFc) Cytokine Receptor Family 2 Member 10 CRF2-10 IL-22R-a-2 IL-22RA2 Interleukin-22 Receptor Subunit α-2 Interleukin-22-Bind IL-22R-α-2 Interleukin-22 Receptor Subunit Alpha-2 IL-22 Receptor Subunit Alpha-2 Cytokine Receptor Family Type 2 Soluble 1 Interleukin-22 Receptor Subunit a-2 IL-22 Receptor Subunit a-2 Cytokine Receptor Class-II Member 10 CRF2-S1 IL-22R-Alpha-2 IL-22 Receptor Subunit α-2 recombinant recombinant-proteins proteins protein