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IL-22RA2 Protein, Human, Recombinant (hFc)

(Synonyms: Interleukin-22-Bind, Interleukin-22 Receptor Subunit α-2, Interleukin-22 Receptor Subunit Alpha-2, IL-22R-α-2, IL-22R-Alpha-2, IL-22RA2, IL-22 Receptor Subunit α-2, IL-22 Receptor Subunit Alpha-2, Cytokine Receptor Family Type 2 Soluble 1, Cytokine Receptor Family 2 Member 10, Cytokine Receptor Class-II Member 10, CRF2-S1, CRF2-10) Copy Product Info

Synonyms: Interleukin-22-Bind, Interleukin-22 Receptor Subunit α-2, Interleukin-22 Receptor Subunit Alpha-2, IL-22R-α-2, IL-22R-Alpha-2, IL-22RA2, IL-22 Receptor Subunit α-2, IL-22 Receptor Subunit Alpha-2, Cytokine Receptor Family Type 2 Soluble 1, Cytokine Receptor Family 2 Member 10, Cytokine Receptor Class-II Member 10, CRF2-S1, CRF2-10

Catalog No. TMPJ-00119 Copy Product Info
Interleukin-22 Receptor Subunit α-2 (IL22RA2) belongs to the type II cytokine receptor family. IL22RA2 is a secreted protein and contains three fibronectin type-III domains. IL22RA2 is widely expressed in many tissues. IL22RA2 functions as an IL22 antagonist and may be important in the regulation of inflammatory response. Three alternatively spliced transcript variants encoding distinct isoforms have been described.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$807-10 days7-10 days
10 µg$1297-10 days7-10 days
20 µg$1987-10 days7-10 days
50 µg$3907-10 days7-10 days
100 µg$6267-10 days7-10 days
200 µg$9877-10 days7-10 days
500 µg$1,9007-10 days7-10 days
1 mg$2,7307-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Immobilized Recombinant Human IL-22 (E. Coli) at 2μg/ml (100 μl/well) can bind Recombinant Human IL-22RA2 (C-Fc). The ED50 of Recombinant Human IL-22RA2 (C-Fc) is 34.43 ng/ml. (Regularly tested)
Description
Interleukin-22 Receptor Subunit α-2 (IL22RA2) belongs to the type II cytokine receptor family. IL22RA2 is a secreted protein and contains three fibronectin type-III domains. IL22RA2 is widely expressed in many tissues. IL22RA2 functions as an IL22 antagonist and may be important in the regulation of inflammatory response. Three alternatively spliced transcript variants encoding distinct isoforms have been described.
Species
Human
Expression System
HEK293 Cells
TagC-hFc
Accession NumberQ969J5-2
Amino AcidThr22-Pro231
ConstructionThr22-Pro231
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsInterleukin-22-Bind, Interleukin-22 Receptor Subunit α-2, Interleukin-22 Receptor Subunit Alpha-2, IL-22R-α-2, IL-22R-Alpha-2, IL-22RA2, IL-22 Receptor Subunit α-2, IL-22 Receptor Subunit Alpha-2, Cytokine Receptor Family Type 2 Soluble 1, Cytokine Receptor Family 2 Member 10, Cytokine Receptor Class-II Member 10, CRF2-S1, CRF2-10
Research Background
Interleukin-22 Receptor Subunit α-2 (IL22RA2) belongs to the type II cytokine receptor family. IL22RA2 is a secreted protein and contains three fibronectin type-III domains. IL22RA2 is widely expressed in many tissues. IL22RA2 functions as an IL22 antagonist and may be important in the regulation of inflammatory response. Three alternatively spliced transcript variants encoding distinct isoforms have been described.
Chemical Properties
Molecular Weight80-100 KDa (reducing condition)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: IL-22RA2 Protein, Human, Recombinant (hFc) chemical structure | IL-22RA2 Protein, Human, Recombinant (hFc) molecular weight