Shopping Cart
- Remove All
Your shopping cart is currently empty
Anti-HRG/HPRG Antibody (1Q55)
😃Good
Catalog No. TMAY-01241
Alias histidine-rich glycoprotein
Anti-HRG/HPRG Antibody (1Q55) is a Rabbit antibody targeting HRG/HPRG. Anti-HRG/HPRG Antibody (1Q55) can be used in ELISA.
Anti-HRG/HPRG Antibody (1Q55)
Anti-HRG/HPRG Antibody (1Q55)
😃Good
Catalog No. TMAY-01241Alias histidine-rich glycoprotein
Anti-HRG/HPRG Antibody (1Q55) is a Rabbit antibody targeting HRG/HPRG. Anti-HRG/HPRG Antibody (1Q55) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
Bulk & Custom
Add to Cart
Questions
View MoreContact us for more batch information
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA Reactivity: Human |
| Alias | histidine-rich glycoprotein |
| Ig Type | Rabbit IgG |
| Clone | 1Q55 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human HPRG (rhHPRG; TMPY-00979; Met 1-Lys 525; NP_000403.1). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Histidine-rich glycoprotein, also known as HRG and HPRG, is a glycoprotein located in plasma and platelets and contains an unusually large amount of histidine and proline. In humans, five distinct domains are recognized in the mature HPRG molecule. There are two N-terminal cystatin-like modules (aa 19 - 254) and one His-Pro-rich region (aa 350 - 497) that is flanked by two Pro-rich segments (aa 276 - 321 and 498 - 525). The His-Pro-rich region contains 10 tandem repeats with an HHPHG motif, and the N- and C-termini are linked by a disulfide bond. The specific functions of HRG remain unclear, but it is known that the protein binds heme, dyes, and divalent metal ions. It inhibits rosette formation and interacts with heparin, thrombospondin, and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis, and the reduction of inhibition of coagulation indicate a potential prothrombotic effect. HPRG is evolutionarily, functionally, and structurally related to cleaved high molecular weight kininogen (HKa), an anti-angiogenic polypeptide that stimulates apoptosis of proliferating endothelial cells through binding to cell-surface tropomyosin. The antiangiogenic activity of the multidomain plasma protein HPRG is localized to its histidine-proline-rich (H/P) domain and has recently been shown to be mediated, at least partially, through binding to cell-surface tropomyosin in fibroblast growth factor-2-activated endothelial cells. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human HPRG protein (TMPY-00979) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
Sci Citations
Calculator
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Anti-HRG/HPRG Antibody (1Q55) | purchase Anti-HRG/HPRG Antibody (1Q55) | Anti-HRG/HPRG Antibody (1Q55) cost | order Anti-HRG/HPRG Antibody (1Q55)
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.