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Nitric Oxide Synthase (599-613) Blocking Peptide, Bovine Endothelial Cell

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Catalog No. TP2195

Nitric Oxide Synthase (599-613) Blocking Peptide, Bovine Endothelial Cell (Ac-Pro-Tyr-Asn-Ser-Ser-Pro-Arg-Pro-Glu-Gln-His-Lys-Ser-Tyr-Lys-Cys) is a peptide that inhibits the function of NOSs as a result it blocks the production of NO. Because of the involvement of all the three NOS isozymes in various aspects of signal transduction, NOS inhibitors have gained prominence in the management of ischemic-reperfusion injury, hypotensive effects of drugs, and inflammatory response to cytokines.

Nitric Oxide Synthase (599-613) Blocking Peptide, Bovine Endothelial Cell

Nitric Oxide Synthase (599-613) Blocking Peptide, Bovine Endothelial Cell

😃Good
Catalog No. TP2195
Nitric Oxide Synthase (599-613) Blocking Peptide, Bovine Endothelial Cell (Ac-Pro-Tyr-Asn-Ser-Ser-Pro-Arg-Pro-Glu-Gln-His-Lys-Ser-Tyr-Lys-Cys) is a peptide that inhibits the function of NOSs as a result it blocks the production of NO. Because of the involvement of all the three NOS isozymes in various aspects of signal transduction, NOS inhibitors have gained prominence in the management of ischemic-reperfusion injury, hypotensive effects of drugs, and inflammatory response to cytokines.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$59InquiryInquiry
5 mg$171InquiryInquiry
10 mg$282InquiryInquiry
25 mg$394InquiryInquiry
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Nitric Oxide Synthase (599-613) Blocking Peptide, Bovine Endothelial Cell (Ac-Pro-Tyr-Asn-Ser-Ser-Pro-Arg-Pro-Glu-Gln-His-Lys-Ser-Tyr-Lys-Cys) is a peptide that inhibits the function of NOSs as a result it blocks the production of NO. Because of the involvement of all the three NOS isozymes in various aspects of signal transduction, NOS inhibitors have gained prominence in the management of ischemic-reperfusion injury, hypotensive effects of drugs, and inflammatory response to cytokines.
Chemical Properties
Molecular Weight1963.13
FormulaC85H127N25O27S
Relative Density.no data available
SequenceAc-DL-Pro-DL-Tyr-DL-Asn-DL-Ser-DL-Ser-DL-Pro-DL-Arg-DL-Pro-DL-Glu-DL-Gln-DL-His-DL-Lys-DL-Ser-DL-Tyr-DL-Lys-DL-Cys-OH
Sequence ShortPYNSSPRPEQHKSYKC
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: ≥196.3 mg/mL, Sonication is recommended.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

Nitric Oxide Synthase (599613) Blocking Peptide, Bovine Endothelial CellNitric Oxide Synthase (599 613) Blocking Peptide, Bovine Endothelial Cell
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