keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Pyridinium bisretinoid A2E (A2E) TFA, a fluorophore derived from retinal pigment epithelium (RPE) lipofuscin, initiates blue-light-induced apoptosis, mediates autophagy, and generates reactive oxygen species. This compound is instrumental in researching retinal degenerative diseases [1] [2].
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Description | Pyridinium bisretinoid A2E (A2E) TFA, a fluorophore derived from retinal pigment epithelium (RPE) lipofuscin, initiates blue-light-induced apoptosis, mediates autophagy, and generates reactive oxygen species. This compound is instrumental in researching retinal degenerative diseases [1] [2]. |
In vitro | Exposure to light induces pyridinium bisretinoid A2E (A2E) to transform into at least two products. One of them is epoxy-A2E, which is hydrophilic and can migrate from membranes into aqueous solutions. The other product is an unidentified hydrophobic substance [3]. |
Synonyms | A2E TFA |
Molecular Weight | 705.93 |
Formula | C44H58F3NO3 |
CAS No. | 1821308-73-9 |
keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Pyridinium bisretinoid A2E TFA 1821308-73-9 Apoptosis A2E TFA inhibitor inhibit