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Pyridinium bisretinoid A2E (A2E) TFA, a fluorophore derived from retinal pigment epithelium (RPE) lipofuscin, initiates blue-light-induced apoptosis, mediates autophagy, and generates reactive oxygen species. This compound is instrumental in researching retinal degenerative diseases [1] [2].

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| 5 mg | Inquiry | Backorder | Backorder | |
| 50 mg | Inquiry | Backorder | Backorder |
| Description | Pyridinium bisretinoid A2E (A2E) TFA, a fluorophore derived from retinal pigment epithelium (RPE) lipofuscin, initiates blue-light-induced apoptosis, mediates autophagy, and generates reactive oxygen species. This compound is instrumental in researching retinal degenerative diseases [1] [2]. |
| In vitro | Exposure to light induces pyridinium bisretinoid A2E (A2E) to transform into at least two products. One of them is epoxy-A2E, which is hydrophilic and can migrate from membranes into aqueous solutions. The other product is an unidentified hydrophobic substance [3]. |
| Synonyms | A2E TFA |
| Molecular Weight | 705.93 |
| Formula | C44H58F3NO3 |
| Cas No. | 1821308-73-9 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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