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Streptomycin
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Catalog No. T75320Cas No. 57-92-1
Alias Agrimycin, Agrept
Streptomycin (Agrept) is an aminoglycoside antibiotic derived from Streptomyces, a blocker of stretch-activated and mechanically-sensitive ion channels in neurons and cardiomyocytes, with anti-tuberculosis activity. It strongly binds to nucleic acids, interferes with protein synthesis, and can be used to study Mycobacterium tuberculosis infections.
Streptomycin
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Purity: 99.99%
Catalog No. T75320Alias Agrimycin, AgreptCas No. 57-92-1
Streptomycin (Agrept) is an aminoglycoside antibiotic derived from Streptomyces, a blocker of stretch-activated and mechanically-sensitive ion channels in neurons and cardiomyocytes, with anti-tuberculosis activity. It strongly binds to nucleic acids, interferes with protein synthesis, and can be used to study Mycobacterium tuberculosis infections.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 mg | $30 | In Stock | In Stock | |
| 100 mg | $40 | In Stock | In Stock | |
| 500 mg | $92 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.99%
Appearance:Solid
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Streptomycin (Agrept) is an aminoglycoside antibiotic derived from Streptomyces, a blocker of stretch-activated and mechanically-sensitive ion channels in neurons and cardiomyocytes, with anti-tuberculosis activity. It strongly binds to nucleic acids, interferes with protein synthesis, and can be used to study Mycobacterium tuberculosis infections. |
| In vitro | Streptomycin is a protein synthesis inhibitor that binds irreversibly to the small 16S rRNA of the 30S ribosome subunit, interfering with the binding of formyl-methionyl-trNA to the 30S subunit. It is often used in combination with penicillin in standard antibiotic mixtures to prevent bacterial infection in cell cultures. [1] |
| In vivo | Administration of Streptomycin (644 ± 26 mg/kg/ day) reduced the number of muscle fibers that increased membrane permeability after centrifugal contraction (ECC), but did not improve the degree of fiber swelling in existing EBD-positive fibers. [2] |
| Synonyms | Agrimycin, Agrept |
| Molecular Weight | 581.57 |
| Formula | C21H39N7O12 |
| Cas No. | 57-92-1 |
| Smiles | O([C@H]1[C@H](O[C@@H]2[C@@H](NC(=N)N)[C@H](O)[C@@H](NC(=N)N)[C@H](O)[C@H]2O)O[C@@H](C)[C@@]1(C=O)O)[C@H]3[C@@H](NC)[C@H](O)[C@@H](O)[C@H](CO)O3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: 247.5 mg/mL (425.57 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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