OBhFc1 Protein, Human, Recombinant (His)

Name: OBhFc1 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-00516
Rating: 4.5 (1 reviews)

(Synonyms: Suppressor of Cdc Thirteen Homolog, STN1, Oligonucleotide/Oligosaccharide-Binding Fold-Containing Protein 1, OBFC1, CST Complex Subunit STN1) Copy Product Info

Synonyms: Suppressor of Cdc Thirteen Homolog, STN1, Oligonucleotide/Oligosaccharide-Binding Fold-Containing Protein 1, OBFC1, CST Complex Subunit STN1

Catalog No. TMPJ-00516 Copy Product Info

CST Complex Subunit STN1 (OBFC1) is a 368 amino acid protein that contains one OB DNA-binding domain. It is a member of the STN1 family. OBFC1 is component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.

OBhFc1 Protein, Human, Recombinant (His)

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Pack Size	Price	USA Stock	Global Stock
5 µg	$112	35 days	35 days
10 µg	$183	35 days	35 days
20 µg	$292	35 days	35 days
50 µg	$545	35 days	35 days
100 µg	$813	35 days	35 days
200 µg	$1,190	35 days	35 days
500 µg	$2,070	35 days	35 days
1 mg	$2,970	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	CST Complex Subunit STN1 (OBFC1) is a 368 amino acid protein that contains one OB DNA-binding domain. It is a member of the STN1 family. OBFC1 is component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.
Species	Human
Expression System	E. coli
Tag	N-6xHis
Accession Number	AAH17400.1
Amino Acid	Met1-Phe368
Construction	Met1-Phe368
Protein Purity	Greater than 80% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-HCl, 1 mM DTT, 5% Trehalose, pH 8.0.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Suppressor of Cdc Thirteen Homolog, STN1, Oligonucleotide/Oligosaccharide-Binding Fold-Containing Protein 1, OBFC1, CST Complex Subunit STN1
Research Background	CST Complex Subunit STN1 (OBFC1) is a 368 amino acid protein that contains one OB DNA-binding domain. It is a member of the STN1 family. OBFC1 is component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.

Chemical Properties

Molecular Weight

44 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.