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OBhFc1 Protein, Human, Recombinant (His)

(Synonyms: Suppressor of Cdc Thirteen Homolog, STN1, Oligonucleotide/Oligosaccharide-Binding Fold-Containing Protein 1, OBFC1, CST Complex Subunit STN1) Copy Product Info

Synonyms: Suppressor of Cdc Thirteen Homolog, STN1, Oligonucleotide/Oligosaccharide-Binding Fold-Containing Protein 1, OBFC1, CST Complex Subunit STN1

Catalog No. TMPJ-00516 Copy Product Info
CST Complex Subunit STN1 (OBFC1) is a 368 amino acid protein that contains one OB DNA-binding domain. It is a member of the STN1 family. OBFC1 is component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.
OBhFc1 Protein, Human, Recombinant (His)
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Pack SizePriceUSA StockGlobal StockQuantity
5 μg$11235 days35 days
10 μg$18335 days35 days
20 μg$29235 days35 days
50 μg$54535 days35 days
100 μg$81335 days35 days
200 μg$1,19035 days35 days
500 μg$2,07035 days35 days
1 mg$2,97035 days35 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
CST Complex Subunit STN1 (OBFC1) is a 368 amino acid protein that contains one OB DNA-binding domain. It is a member of the STN1 family. OBFC1 is component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.
Species
Human
Expression System
E. coli
TagN-6xHis
Accession NumberAAH17400.1
Amino AcidMet1-Phe368
ConstructionMet1-Phe368
Protein Purity
Greater than 80% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-HCl, 1 mM DTT, 5% Trehalose, pH 8.0.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsSuppressor of Cdc Thirteen Homolog, STN1, Oligonucleotide/Oligosaccharide-Binding Fold-Containing Protein 1, OBFC1, CST Complex Subunit STN1
Research Background
Chemical Properties
Molecular Weight44 KDa (reducing condition)
Storage & Solubility Information
StorageLyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Keywords

Related Tags: OBhFc1 Protein, Human, Recombinant (His) chemical structure | OBhFc1 Protein, Human, Recombinant (His) molecular weight