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Synonyms: Progestin and adipoQ receptor family member II, PAQR2, ADR2, Adipor2, Adiponectin receptor 2, Adipo R2
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
| Description | Anti-ADIPOR2 Polyclonal Antibody is a Rabbit antibody targeting ADIPOR2. Anti-ADIPOR2 Polyclonal Antibody can be used in FCM,IF,IHC-Fr,IHC-P,WB. |
| Synonyms | Progestin and adipoQ receptor family member II, PAQR2, ADR2, Adipor2, Adiponectin receptor 2, Adipo R2 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Chicken,Dog,Pig,Cow) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg /test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Multi-pass membrane protein. Note=Localized to the cell membrane and intracellular organelles. |
| Tissue Specificity | Highly expressed in skeletal muscle, liver and placenta. Weakly expressed in brain, heart, colon, spleen, kidney, thymus, small intestine, peripheral blood leukocytes and lung. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The adiponectin receptors, ADIPOR1 (MIM 607945) and ADIPOR2, serve as receptors for globular and full-length adiponectin (MIM 605441) and mediate increased AMPK (see MIM 602739) and PPAR-alpha (PPARA; MIM 170998) ligand activities, as well as fatty acid oxidation and glucose uptake by adiponectin (Yamauchi et al., 2003 [PubMed 12802337]).[supplied by OMIM, Mar 2008] |
| Immunogen | KLH conjugated synthetic peptide: human Adiponectin receptor 2 |
| Antigen Species | Human |
| Gene Name | ADIPOR2 |
| Gene ID | |
| Protein Name | Adiponectin receptor protein 2 |
| Uniprot ID | |
| Biology Area | Lipid metabolism,Energy Metabolism,Hormones,Heart disease,Diabetes,Cancer,Fatty acid oxidation,Lipoprotein metabolism,Fatty acids,Energy Metabolism,Metabolism,Lipoprotein metabolism,Diabetes associated |
| Function | Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some intermediate-affinity receptor activity for both globular and full-length adiponectin. |
| Molecular Weight | Theoretical: 44 kDa. Actual: 43 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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