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Anti-ADIPOR2 Polyclonal Antibody

(Synonyms: Progestin and adipoQ receptor family member II, PAQR2, ADR2, Adipor2, Adiponectin receptor 2, Adipo R2) Copy Product Info
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Synonyms: Progestin and adipoQ receptor family member II, PAQR2, ADR2, Adipor2, Adiponectin receptor 2, Adipo R2

Catalog No. TMAB-00065 Copy Product Info
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Anti-ADIPOR2 Polyclonal Antibody is a Rabbit antibody targeting ADIPOR2. Anti-ADIPOR2 Polyclonal Antibody can be used in FCM,IF,IHC-Fr,IHC-P,WB.
Anti-ADIPOR2 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-ADIPOR2 Polyclonal Antibody is a Rabbit antibody targeting ADIPOR2. Anti-ADIPOR2 Polyclonal Antibody can be used in FCM,IF,IHC-Fr,IHC-P,WB.
SynonymsProgestin and adipoQ receptor family member II, PAQR2, ADR2, Adipor2, Adiponectin receptor 2, Adipo R2
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Chicken,Dog,Pig,Cow)
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg /test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Multi-pass membrane protein. Note=Localized to the cell membrane and intracellular organelles.
Tissue SpecificityHighly expressed in skeletal muscle, liver and placenta. Weakly expressed in brain, heart, colon, spleen, kidney, thymus, small intestine, peripheral blood leukocytes and lung.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundThe adiponectin receptors, ADIPOR1 (MIM 607945) and ADIPOR2, serve as receptors for globular and full-length adiponectin (MIM 605441) and mediate increased AMPK (see MIM 602739) and PPAR-alpha (PPARA; MIM 170998) ligand activities, as well as fatty acid oxidation and glucose uptake by adiponectin (Yamauchi et al., 2003 [PubMed 12802337]).[supplied by OMIM, Mar 2008]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Adiponectin receptor 2
Antigen Species
Human
Gene Name
ADIPOR2
Gene ID
Protein Name
Adiponectin receptor protein 2
Uniprot ID
Biology Area
Lipid metabolism,Energy Metabolism,Hormones,Heart disease,Diabetes,Cancer,Fatty acid oxidation,Lipoprotein metabolism,Fatty acids,Energy Metabolism,Metabolism,Lipoprotein metabolism,Diabetes associated
Function
Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some intermediate-affinity receptor activity for both globular and full-length adiponectin.
Chemical Properties
Molecular WeightTheoretical: 44 kDa. Actual: 43 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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