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Anti-PRLR Polyclonal Antibody
😃Good
Catalog No. TMAB-01574
Alias prolactin receptor, PRLR, MFAB, hPRLrI, HPRL
Anti-PRLR Polyclonal Antibody is a Rabbit antibody targeting PRLR. Anti-PRLR Polyclonal Antibody can be used in WB.
Anti-PRLR Polyclonal Antibody
Anti-PRLR Polyclonal Antibody
😃Good
Catalog No. TMAB-01574Alias prolactin receptor, PRLR, MFAB, hPRLrI, HPRL
Anti-PRLR Polyclonal Antibody is a Rabbit antibody targeting PRLR. Anti-PRLR Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-PRLR Polyclonal Antibody is a Rabbit antibody targeting PRLR. Anti-PRLR Polyclonal Antibody can be used in WB. |
| Synonyms | prolactin receptor, PRLR, MFAB, hPRLrI, HPRL |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat) |
| Verified Activity | 1. Sample: Brain (Mouse) Lysate at 40 μg Primary: Anti-PRLR (TMAB-01574) at 1/300 dilution Secondary: HRP conjugated Goat-Anti-rabbit IgG (secondary antibody) at 1/5000 dilution Predicted band size: 67 kDa Observed band size: 67 kDa 2. Paraformaldehyde-fixed, paraffin embedded (Mouse pancreas); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (PRLR) Polyclonal Antibody, Unconjugated (TMAB-01574) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining.   |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. Isoform 7: Secreted. |
| Tissue Specificity | Expressed in breast, placenta, kidney, liver and pancreas. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011]. |
| Immunogen | KLH conjugated synthetic peptide: human Prolactin Receptor |
| Antigen Species | Human |
| Gene Name | PRLR |
| Gene ID | |
| Protein Name | Prolactin receptor |
| Uniprot ID | |
| Biology Area | Cancer,Hormones,Lipid metabolism,Receptor Tyrosine Kinases |
| Function | This is a receptor for the anterior pituitary hormone prolactin (PRL). Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling. |
| Molecular Weight | Theoretical: 67 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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