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Anti-NMDAR3A Polyclonal Antibody

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Catalog No. TMAB-01249

Anti-NMDAR3A Polyclonal Antibody is a Rabbit antibody targeting NMDAR3A. Anti-NMDAR3A Polyclonal Antibody can be used in WB.

Anti-NMDAR3A Polyclonal Antibody

Anti-NMDAR3A Polyclonal Antibody

😃Good
Catalog No. TMAB-01249
Anti-NMDAR3A Polyclonal Antibody is a Rabbit antibody targeting NMDAR3A. Anti-NMDAR3A Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$220 7-10 days
100 μL$373 7-10 days
200 μL$529 7-10 days
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Product Introduction

Bioactivity
Description
Anti-NMDAR3A Polyclonal Antibody is a Rabbit antibody targeting NMDAR3A. Anti-NMDAR3A Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Dog,Rabbit)
Verified Activity
1. Sample: Placenta (Mouse) lysate at 40 μg
Primary: Anti-NMDAR3a (TMAB-01249) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 123 kDa
Observed band size: 123 kDa
2. Sample:
Testis (Mouse) Lysate at 40 μg
Primary: Anti-NMDAR3A (TMAB-01249) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 123 kDa
Observed band size: 123 kDa
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Multi-pass membrane protein (By similarity). Cell junction, synapse, postsynaptic cell membrane (By similarity). Cell junction, synapse, postsynaptic cell membrane, postsynaptic density (By similarity). Note=Enriched in postsynaptic plasma membrane and postsynaptic densities. Requires the presence of GRIN1 to be targeted at the plasma membrane
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundGlutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neuro-degeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors co-localize with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to 7. The kainate/AMPA receptors are primarily responsible for fast excitatory neurotransmission by glutamate, whereas the NMDA receptors exhibit slow kinesis of Ca2+ ions and a high permeability for Ca2+ ions. One such NMDA receptor, NR3B, is expressed in motor neurons and forms cation channels impermeable to calcium, which can resist many open-channel blockers. NR3B functions in the brain as an excitatory glycine receptor, modifying the normal role of glycine as an inhibitory neurotransmitter.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human NMDAR3A/NR3A
Antigen Species
Human
Gene ID
Uniprot ID
Biology Area
NMDA Receptors
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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