Shopping Cart
Remove All
Your shopping cart is currently empty
(60)
AutophagyLRRK2
Leucine-rich repeat kinase 2 (LRRK2), also known as dardarin (from the Basque word "dardara" which means trembling) and PARK8 (from early identified association with Parkinson's disease), is a kinase enzyme that in humans is encoded by the LRRK2 gene. LRRK2 is a member of the leucine-rich repeat kinase family. Variants of this gene are associated with an increased risk of Parkinson's disease and also Crohn's disease.
LRRK2-IN-7
T731762307277-93-4In house
LRRK2-IN-7 is a selective, CNS permeable and potent LRRK2 kinase inhibitor (IC50: 0.9 nM) for the study of Parkinson's disease.
- $239
Size
QTY
MLi-2
T161151627091-47-7
MLi-2 is a structurally novel, highly potent, and selective LRRK2 kinase inhibitor with central nervous system activity. MLi-2 exhibits exceptional potency in a purified LRRK2 kinase assay in vitro (IC50 = 0.76 nM), a cellular assay monitoring dephosphorylation of LRRK2 pSer935 LRRK2 (IC50 = 1.4 nM), and a radioligand competition binding assay (IC50 = 3.4 nM).
- $53
Size
QTY
IKK 16
Cited
IKK-16, IKK16, IKK Inhibitor VII
T6176873225-46-8
IKK 16 (IKK Inhibitor VII) is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.
- $34
Size
QTY
CitedURMC-099
T60571229582-33-5
URMC-099 is an orally bioavailable, brain penetrant MLK inhibitor (IC50: 19/42/14/150 nM, for MLK1/MLK2/MLK3/DLK), and also inhibits LRRK2 activity (IC50: 11 nM).
Aurora KinaseAutophagyBcr-AblCDKc-Met/HGFRDNA AlkylationIGF-1RLRRK2MEKMLKROCKSGKSrcSykTrk receptorVEGFR
- $52
Size
QTY
GNE0877
GNE-0877, GNE 0877
T60311374828-69-9
GNE0877 (GNE 0877) is a highly effective and specific leucine-rich repeat kinase 2 (LRRK2) inhibitor (Ki: 0.7 nM).
- $39
Size
QTY
CCG-1423 Cited
CCG1423
T2014285986-88-1
CCG-1423, a selective RhoA pathway inhibitor, suppresses SRF-mediated transcription.
- $32
Size
QTY
CitedPF-06447475
T20501527473-33-1
PF-06447475 is a highly effective, specific, brain penetrant LRRK2 inhibitor with IC0 of 3/11 nM for wild type LRRK2 and G2019S LRRK2 respectively.
- $43
Size
QTY
LRRK2-IN-1 Cited
T22461234480-84-2
LRRK2-IN-1 is an effective and selective LRRK2 inhibitor.
- $60
Size
QTY
CitedHG-10-102-01
T71961351758-81-0
HG-10-102-01 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2, IC50 of 20.3 nM).
- $32
Size
QTY
LRRK2 inhibitor 1
T118781802525-61-6In house
LRRK2 inhibitor 1 is a selective and potent LRRK2 inhibitor with an IC50 of 13 nM.LRRK2 inhibitor 1 inhibits DCLK1 kinase with an IC50 value of 2.61 nM.
- $68
Size
QTY
PFE-360
PF-06685360
T165121527475-61-1
PFE-360 (PF-06685360) is a potent and selective inhibitor of LRRK2 kinase, with an in vivo IC50 of 2.3 nM.
- $68
Size
QTY
CZC-54252
CZC54252, CZC 54252
T20221191911-27-9
CZC-54252 is a potent inhibitor of LRRK2.
- $32
Size
QTY
GSK2578215A
T22401285515-21-0
GSK2578215A is a potent and selective LRRK2 kinase inhibitor.
- $29
Size
QTY
CZC-54252 hydrochloride
T392021784253-05-9
CZC-54252 hydrochloride is a selective inhibitor of LRRK2 with IC50s of 1.85 nM and 1.28 nM for wild-type and G2019S LRRK2. CZC-54252 hydrochloride has a neuroprotective activity and attenuates G2019S LRRK2-induced human neuronal injury with an EC50 of 1 nM.
- $36
Size
QTY
CZC-25146 hydrochloride
T51391330003-04-7
CZC-25146 is a selective LRRK2 inhibitor with IC50 of 4.76 nM/6.87 nM for wild type LRRK2 and G2019S LRRK2, respectively.
- $30
Size
QTY
GNE-7915
GNE7915
T19451351761-44-8
GNE-7915 is a highly potent, selective and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) inhibitor.
- $39
Size
QTY
Indazole
Cited
T2192271-44-3
Indazole is also called benzpyrazole or isoindazone. Its derivatives exhibit a wide range of biological activities. Indazole and its derivatives can be used in the research of cancer, neurological diseases, cardiovascular diseases, and gastrointestinal diseases.
- $29
Size
QTY
CitedCZC-25146
CHEMBL2397014
T30531191911-26-8
CZC-25146 (CHEMBL2397014) is an effective, specific and metabolically stable LRRK2 inhibitor with IC50 of 4.76/6.87 nM for wild-type LRRK2(Leucine-rich repeat kinase-2) and G2019S LRRK2, respectively.
- $48
Size
QTY
RN277
T210823
RN277 is an inhibitor of LRRK2 type II kinase (LRRK2type II kinase). It serves as a cellular tool targeting the inactive state of LRRK2. In vitro, RN277 inhibits LRRK1 kinase activity and the kinase activity of LRRK2, with an IC50 of 70 nM. Additionally, it reduces Rab8a phosphorylation in a dose-dependent manner. RN277 is useful for Parkinson's disease research.
- Inquiry Price
Size
QTY
Go to page 1
Page of 2
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.