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Anti-ENPP2 Antibody (5B899)
😃Good
Catalog No. TMAY-01839
Alias PDNP2, PD-Iα, PD-IALPHA, NPP2, LysoPLD, ectonucleotide pyrophosphatase/phosphodiesterase 2, AUTOTAXIN, ATX-X, ATX
Anti-ENPP2 Antibody (5B899) is a Mouse antibody targeting ENPP2. Anti-ENPP2 Antibody (5B899) can be used in ELISA.
Anti-ENPP2 Antibody (5B899)
Anti-ENPP2 Antibody (5B899)
😃Good
Catalog No. TMAY-01839Alias PDNP2, PD-Iα, PD-IALPHA, NPP2, LysoPLD, ectonucleotide pyrophosphatase/phosphodiesterase 2, AUTOTAXIN, ATX-X, ATX
Anti-ENPP2 Antibody (5B899) is a Mouse antibody targeting ENPP2. Anti-ENPP2 Antibody (5B899) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA Reactivity: Human |
| Alias | PDNP2, PD-Iα, PD-IALPHA, NPP2, LysoPLD, ectonucleotide pyrophosphatase/phosphodiesterase 2, AUTOTAXIN, ATX-X, ATX |
| Ig Type | Mouse IgG2b |
| Clone | 5B899 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Autotaxin/ENPP2 (rh Autotaxin/ENPP2; TMPY-02778; AAH34961.1; Asp49-Ile863). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | ENPP2 (Ectonucleotide pyrophosphatase/phosphodiesterase family member 2), also referred as Autotaxin, is a secreted enzyme encoded by the ENPP2 gene. This gene product stimulates the motility of tumor cells, has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The Autotaxin protein is important for generating the lipid signaling molecule lysophosphatidic acid (LPA), which is a potent mitogen, which facilitates cell proliferation and migration, neurite retraction, platelet aggregation, smooth muscle contraction, actin stress formation and cytokine and chemokine secretion. ATX has been found to catalyze the formation of cyclic phosphatidic acid (cPA), which have antitumor role by antimitogenic regulation of cell cycle, inhibition of cancer invasion and metastasis. LPA receptors and ATX are upregulated in numerous cancer cell types and show expression patterns that correlate with tumor cell invasiveness. Thus, Autotaxin has recently emerged as an attractive target for the development of anti-cancer chemotherapeutics. In addition, Serum ATX activity was found to be enhanced in relation to hepatic fibrosis in chronic liver disease due to hepatitis virus C infection. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human Autotaxin/ENPP2 Protein (TMPY-02778) |
| Antigen Species | Human |
| Biology Area | Phosphatases and Regulators |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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