Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-ENPP2 Antibody (5B899)

😃Good
Catalog No. TMAY-01839
Alias PDNP2, PD-Iα, PD-IALPHA, NPP2, LysoPLD, ectonucleotide pyrophosphatase/phosphodiesterase 2, AUTOTAXIN, ATX-X, ATX

Anti-ENPP2 Antibody (5B899) is a Mouse antibody targeting ENPP2. Anti-ENPP2 Antibody (5B899) can be used in ELISA.

Anti-ENPP2 Antibody (5B899)

Anti-ENPP2 Antibody (5B899)

😃Good
Catalog No. TMAY-01839Alias PDNP2, PD-Iα, PD-IALPHA, NPP2, LysoPLD, ectonucleotide pyrophosphatase/phosphodiesterase 2, AUTOTAXIN, ATX-X, ATX
Anti-ENPP2 Antibody (5B899) is a Mouse antibody targeting ENPP2. Anti-ENPP2 Antibody (5B899) can be used in ELISA.
Pack SizePriceAvailabilityQuantity
100 μL$198 7-10 days
Bulk & Custom
Add to Cart
Questions
View More
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Anti-ENPP2 Antibody (5B899) is a Mouse antibody targeting ENPP2. Anti-ENPP2 Antibody (5B899) can be used in ELISA.
AliasPDNP2, PD-Iα, PD-IALPHA, NPP2, LysoPLD, ectonucleotide pyrophosphatase/phosphodiesterase 2, AUTOTAXIN, ATX-X, ATX
Ig Type
Monoclonal Mouse IgG2b
Clone
5B899
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Autotaxin/ENPP2 (rh Autotaxin/ENPP2; TMPY-02778; AAH34961.1; Asp49-Ile863). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundENPP2 (Ectonucleotide pyrophosphatase/phosphodiesterase family member 2), also referred as Autotaxin, is a secreted enzyme encoded by the ENPP2 gene. This gene product stimulates the motility of tumor cells, has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The Autotaxin protein is important for generating the lipid signaling molecule lysophosphatidic acid (LPA), which is a potent mitogen, which facilitates cell proliferation and migration, neurite retraction, platelet aggregation, smooth muscle contraction, actin stress formation and cytokine and chemokine secretion. ATX has been found to catalyze the formation of cyclic phosphatidic acid (cPA), which have antitumor role by antimitogenic regulation of cell cycle, inhibition of cancer invasion and metastasis. LPA receptors and ATX are upregulated in numerous cancer cell types and show expression patterns that correlate with tumor cell invasiveness. Thus, Autotaxin has recently emerged as an attractive target for the development of anti-cancer chemotherapeutics. In addition, Serum ATX activity was found to be enhanced in relation to hepatic fibrosis in chronic liver disease due to hepatitis virus C infection.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human Autotaxin/ENPP2 Protein (TMPY-02778)
Antigen Species
Human
Biology Area
Phosphatases and Regulators
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

Sci Citations

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Anti-ENPP2 Antibody (5B899) | purchase Anti-ENPP2 Antibody (5B899) | Anti-ENPP2 Antibody (5B899) cost | order Anti-ENPP2 Antibody (5B899)