Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Antileishmanial agent-22 (compound 15b) serves as an antiparasitic and antibacterial, exhibiting activities against Leishmania (IC50 = 0.408 μM), malaria, and tuberculosis. It operates on an antifolate mechanism, suppressing both folic and folinic acids with 88% and 94% efficacy at 100 μM, respectively. This compound also demonstrates a 96.67% inhibitory effect on P. berghei in vivo/in vitro at 48.4 μM/kg/day and 0.038 μM (IC50), and it inhibits M. tuberculosis with an MIC of 28.44 μM [1].
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50 mg | Inquiry | Inquiry |
Description | Antileishmanial agent-22 (compound 15b) serves as an antiparasitic and antibacterial, exhibiting activities against Leishmania (IC50 = 0.408 μM), malaria, and tuberculosis. It operates on an antifolate mechanism, suppressing both folic and folinic acids with 88% and 94% efficacy at 100 μM, respectively. This compound also demonstrates a 96.67% inhibitory effect on P. berghei in vivo/in vitro at 48.4 μM/kg/day and 0.038 μM (IC50), and it inhibits M. tuberculosis with an MIC of 28.44 μM [1]. |
Molecular Weight | 549.45 |
Formula | C29H26Cl2N4O3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Antileishmanial agent-22 Microbiology/Virology Parasite inhibitor inhibit