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Anti-PDE2A Antibody (3F805) (Synonyms: phosphodiesterase 2A, cGMP-stimulated, PED2A4, PDE2A1, CGS-PDE, cGSPD...)

Catalog No. TMAH-00867 Copy Product Info
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Anti-PDE2A Antibody (3F805) is an antibody targeting PDE2A. Anti-PDE2A Antibody (3F805) can be used in ELISA,IF.

Anti-PDE2A Antibody (3F805)

Copy Product Info
🥰Excellent
Catalog No. TMAH-00867
Synonyms phosphodiesterase 2A, cGMP-stimulated, PED2A4, PDE2A1, CGS-PDE, cGSPDE

Anti-PDE2A Antibody (3F805) is an antibody targeting PDE2A. Anti-PDE2A Antibody (3F805) can be used in ELISA,IF.

Anti-PDE2A Antibody
(3F805)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2077-10 days7-10 days
100 μL$3477-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-PDE2A Antibody (3F805) is an antibody targeting PDE2A. Anti-PDE2A Antibody (3F805) can be used in ELISA,IF.
Synonymsphosphodiesterase 2A, cGMP-stimulated, PED2A4, PDE2A1, CGS-PDE, cGSPDE
Ig Type
Rabbit IgG
Clone
3F805
Reactivity
Human
Verified Activity
Immunofluorescence staining of HepG2 cell with TMAH-00867 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 569-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Application
Recommended Dose
IF:1:50-1:200.
Antibody Type
Monoclonal
Subcellular Localization[Isoform PDE2A3]: Cell membrane; Lipid-anchor.; [Isoform PDE2A2]: Mitochondrion matrix. Mitochondrion inner membrane. Mitochondrion outer membrane.; [Isoform PDE2A1]: Cytoplasm.; [Isoform 5]: Mitochondrion.
Tissue SpecificityExpressed in brain and to a lesser extent in heart, placenta, lung, skeletal muscle, kidney and pancreas.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundCyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Plays an important role in growth and invasion of malignant melanoma cells (e.g. pseudomyxoma peritonei (PMP) cell line). Regulates mitochondrial cAMP levels and respiration. Involved in the regulation of mitochondria morphology/dynamics and apoptotic cell death via local modulation of cAMP/PKA signaling in the mitochondrion, including the monitoring of local cAMP levels at the outer mitochondrial membrane and of PKA-dependent phosphorylation of DNM1L.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human PDE2A
Antigen Species
Human
Gene Name
PDE2A
Gene ID
Uniprot ID
Biology Area
Signal transduction
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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