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Anti-PDE2A Antibody (3F805)
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Catalog No. TMAH-00867
Alias phosphodiesterase 2A, cGMP-stimulated, PED2A4, PDE2A1, CGS-PDE, cGSPDE
Anti-PDE2A Antibody (3F805) is an antibody targeting PDE2A. Anti-PDE2A Antibody (3F805) can be used in ELISA, IF.
Anti-PDE2A Antibody (3F805)
Anti-PDE2A Antibody (3F805)
😃Good
Catalog No. TMAH-00867Alias phosphodiesterase 2A, cGMP-stimulated, PED2A4, PDE2A1, CGS-PDE, cGSPDE
Anti-PDE2A Antibody (3F805) is an antibody targeting PDE2A. Anti-PDE2A Antibody (3F805) can be used in ELISA, IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $207 | 7-10 days | |
| 100 μL | $347 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Recombinant Rabbit Monoclonal Application: ELISA, IF Reactivity: Human |
| Alias | phosphodiesterase 2A, cGMP-stimulated, PED2A4, PDE2A1, CGS-PDE, cGSPDE |
| Ig Type | Rabbit IgG |
| Clone | 3F805 |
| Reactivity | Human |
| Verified Activity | Immunofluorescence staining of HepG2 cell with TMAH-00867 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 569-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Application | ELISA, IF |
| Recommended Dose | IF:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | [Isoform PDE2A3]: Cell membrane; Lipid-anchor.; [Isoform PDE2A2]: Mitochondrion matrix. Mitochondrion inner membrane. Mitochondrion outer membrane.; [Isoform PDE2A1]: Cytoplasm.; [Isoform 5]: Mitochondrion. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Plays an important role in growth and invasion of malignant melanoma cells (e.g. pseudomyxoma peritonei (PMP) cell line). Regulates mitochondrial cAMP levels and respiration. Involved in the regulation of mitochondria morphology/dynamics and apoptotic cell death via local modulation of cAMP/PKA signaling in the mitochondrion, including the monitoring of local cAMP levels at the outer mitochondrial membrane and of PKA-dependent phosphorylation of DNM1L. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human PDE2A |
| Antigen Species | Human |
| Gene ID | 5138 |
| Uniprot ID | |
| Biology Area | Signal transduction |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Sci Citations
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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