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Anti-Mouse CTLA-4/CD152 (LALA-PG) Antibody (9D9) is a mouse-derived inhibitory antibody targeting mouse CTLA-4/CD152. The Fc fragment carries the LALA-PG mutation, which abolishes binding to endogenous Fcγ receptors. It has been applied in cancer and immunology-related research, such as colon cancer.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $179 | 2-4 weeks | 2-4 weeks | |
| 5 mg | $538 | 2-4 weeks | 2-4 weeks | |
| 10 mg | Preferential | 2-4 weeks | 2-4 weeks |
| Description | Anti-Mouse CTLA-4/CD152 (LALA-PG) Antibody (9D9) is a mouse-derived inhibitory antibody targeting mouse CTLA-4/CD152. The Fc fragment carries the LALA-PG mutation, which abolishes binding to endogenous Fcγ receptors. It has been applied in cancer and immunology-related research, such as colon cancer. |
| In vivo | Anti-Mouse CTLA-4/CD152 (LALA-PG) Antibody (9D9), administered via intraperitoneal injection with a dose of 500 μg 1 day before injection, and 250 μg each on day 2 and day 5, can significantly increase the numbers of regulatory T cells, T follicular helper cells and T follicular regulatory cells in NP2W1S-GFP transplanted mice [1]. Anti-Mouse CTLA-4/CD152 (LALA-PG) Antibody (9D9), administered as a single intraperitoneal injection at a dose of 15 mg/kg, exhibited significant antitumor activity in mice with the colon 26 colon tumor model [2]. |
| Synonyms | 9D9 |
| Clone | 9D9 |
| Reactivity | Mouse |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Target | CTLA-4/CD152(LALA-PG) |
| Storage | Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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