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Anti-Mouse CTLA-4/CD152 (LALA-PG) Antibody (9D9)

(Synonyms: 9D9) Copy Product Info
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Synonyms: 9D9

Catalog No. T9901A-848 Copy Product Info
Purity: 95%
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Anti-Mouse CTLA-4/CD152 (LALA-PG) Antibody (9D9) is a mouse-derived inhibitory antibody targeting mouse CTLA-4/CD152. The Fc fragment carries the LALA-PG mutation, which abolishes binding to endogenous Fcγ receptors. It has been applied in cancer and immunology-related research, such as colon cancer.

Anti-Mouse CTLA-4/CD152
(LALA-PG) Antibody
(9D9)

Pack SizePriceUSA StockGlobal StockQuantity
1 mg$1792-4 weeks2-4 weeks
5 mg$5382-4 weeks2-4 weeks
10 mgPreferential2-4 weeks2-4 weeks
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:95%
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Anti-Mouse CTLA-4/CD152 (LALA-PG) Antibody (9D9) is a mouse-derived inhibitory antibody targeting mouse CTLA-4/CD152. The Fc fragment carries the LALA-PG mutation, which abolishes binding to endogenous Fcγ receptors. It has been applied in cancer and immunology-related research, such as colon cancer.
In vivo
Anti-Mouse CTLA-4/CD152 (LALA-PG) Antibody (9D9), administered via intraperitoneal injection with a dose of 500 μg 1 day before injection, and 250 μg each on day 2 and day 5, can significantly increase the numbers of regulatory T cells, T follicular helper cells and T follicular regulatory cells in NP2W1S-GFP transplanted mice [1].
Anti-Mouse CTLA-4/CD152 (LALA-PG) Antibody (9D9), administered as a single intraperitoneal injection at a dose of 15 mg/kg, exhibited significant antitumor activity in mice with the colon 26 colon tumor model [2].
Synonyms9D9
Clone
9D9
Reactivity
Mouse
Application
FACS
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
TargetCTLA-4/CD152(LALA-PG)
Storage & Solubility Information
StorageStore at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Anti-Mouse CTLA-4/CD152 (LALA-PG) Antibody (9D9) in vivo