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Anti-GPRC5D Antibody (6J802) is a Mouse antibody targeting GPRC5D. Anti-GPRC5D Antibody (6J802) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $199 | 7-10 days |
Description | Anti-GPRC5D Antibody (6J802) is a Mouse antibody targeting GPRC5D. Anti-GPRC5D Antibody (6J802) can be used in ELISA. |
Alias | GPRC5D |
Ig Type | Monoclonal Mouse IgG2b |
Clone | 6J802 |
Reactivity | Human |
Verified Activity | Measured by its binding ability in a functional ELISA. Immobilized Human GPRC5D-VLP protein at 5 μg/mL (100 μL/well) can bind GPRC5D Antibody, Mouse MAb, the EC50is 0.5-5 ng/mL. The VLP isotype control Protein is the negative control. |
Application | ELISA |
Recommended Dose | ELISA: 1:1000-1:2000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human GPRC5D. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Orphan G-protein-coupled receptor family C group 5 member D (GPRC5D) has seven transmembrane segments forming the core of the receptor, as well as an intracellular C-tail and an extracellular N-terminal domain. GPRC5D is highly and selectively expressed on the surface of CD138+ multiple myeloma (MM) cells, whereas in normal tissues, a much lower expression is limited to plasma cells and certain hard keratinizing tissues. This makes GPRC5D a promising marker for monitoring tumor load and a target antigen for MM-specific T cell-engaging therapies such as bispecific antibodies and CAR-T cells. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human GPRC5D Protein |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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