Powder: -20°C for 3 years | In solvent: -80°C for 1 year
1-Octadecyl lysophosphatidic acid (1-octadecyl LPA) is a LPA analog containing stearic acid at the sn-1 position. LPA binds to one of five different G protein linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility. Alkyl ether-linked LPA derivatives have a higher platelet aggregating activity than the acyl derivatives, most likely stemming from an alkyl-specific LPA receptor. For example, 1-octadecyl LPA has a platelet aggregating EC50 value of 9 nM versus 1-octadecanoyl LPA which has an EC50 value of 177 nM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 μg | 35 days | $ 65.00 | |
1 mg | 35 days | $ 123.00 | |
5 mg | 35 days | $ 480.00 | |
10 mg | 35 days | $ 830.00 |
Description | 1-Octadecyl lysophosphatidic acid (1-octadecyl LPA) is a LPA analog containing stearic acid at the sn-1 position. LPA binds to one of five different G protein linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility. Alkyl ether-linked LPA derivatives have a higher platelet aggregating activity than the acyl derivatives, most likely stemming from an alkyl-specific LPA receptor. For example, 1-octadecyl LPA has a platelet aggregating EC50 value of 9 nM versus 1-octadecanoyl LPA which has an EC50 value of 177 nM. |
Molecular Weight | 424.559 |
Formula | C21H45O6P |
CAS No. | 52977-29-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL
Ethanol: 10 mg/mL
Ethanol:PBS (pH 7.2) ((1:1): 0.5 mg/mL
DMF: 10 mg/mL
You can also refer to dose conversion for different animals. More
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1-Octadecyl Lysophosphatidic Acid 52977-29-4 1 Octadecyl Lysophosphatidic Acid 1Octadecyl Lysophosphatidic Acid inhibitor inhibit