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Anti-Phospho-CDC25B (Ser353) Polyclonal Antibody
(Synonyms: p-CDC25B (Ser353), p-CDC25B (S353), CDC25B (p-Ser353), CDC25B (p-S353)) Copy Product Info
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Synonyms: p-CDC25B (Ser353), p-CDC25B (S353), CDC25B (p-Ser353), CDC25B (p-S353)
Catalog No. TMAC-00761 Copy Product Info
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Anti-Phospho-CDC25B (Ser353) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CDC25B (Ser353). Anti-Phospho-CDC25B (Ser353) Polyclonal Antibody can be used in WB.
Anti-Phospho-CDC25B
(Ser353) Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 µL | $217 | 7-10 days | 7-10 days | |
| 100 µL | $318 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
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Related Conjugates and Formulations
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| Description | Anti-Phospho-CDC25B (Ser353) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CDC25B (Ser353). Anti-Phospho-CDC25B (Ser353) Polyclonal Antibody can be used in WB. |
| Synonyms | p-CDC25B (Ser353), p-CDC25B (S353), CDC25B (p-Ser353), CDC25B (p-S353) |
| Ig Type | IgG |
| Reactivity | Human,Mouse |
| Verified Activity | 1. Western blot analysis of extracts from COS7 cells treated with Etoposide using Phospho-CDC25B (Ser353) antibody TMAC-00761. The lane on the right is treated with the antigen-specific peptide.  |
| Application | |
| Recommended Dose | WB: 1:500-1000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Cdc25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of serine 353(R-R-S(p)-V-T) derived from Human CDC25B |
| Antigen Species | Human |
| Uniprot ID |
| Molecular Weight | Actual: 64 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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