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Anti-Phospho-Tyk2 (Tyr1054, 1055) Polyclonal Antibody (Synonyms: Tyk2 (p-Y1054, 1055), Tyk2 (p-Tyr1054, 1055)||...)

Catalog No. TMAB-01526 Copy Product Info
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Anti-Phospho-Tyk2 (Tyr1054, 1055) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Tyk2 (Tyr1054, 1055). Anti-Phospho-Tyk2 (Tyr1054, 1055) Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.

Anti-Phospho-Tyk2 (Tyr1054, 1055) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-01526
Synonyms Tyk2 (p-Y1054, 1055), Tyk2 (p-Tyr1054, 1055), TYK2, p-Tyk2 (Y1054, 1055), p-Tyk2 (Tyr1054, 1055), Non-receptor tyrosine-protein kinase TYK2

Anti-Phospho-Tyk2 (Tyr1054, 1055) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Tyk2 (Tyr1054, 1055). Anti-Phospho-Tyk2 (Tyr1054, 1055) Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.

Anti-Phospho-Tyk2
(Tyr1054, 1055) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-Tyk2 (Tyr1054, 1055) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Tyk2 (Tyr1054, 1055). Anti-Phospho-Tyk2 (Tyr1054, 1055) Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.
SynonymsTyk2 (p-Y1054, 1055), Tyk2 (p-Tyr1054, 1055), TYK2, p-Tyk2 (Y1054, 1055), p-Tyk2 (Tyr1054, 1055), Non-receptor tyrosine-protein kinase TYK2
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Dog)
Verified Activity
1. Sample:
A549 (Human) Cell Lysate at 30 μg
Primary: Anti-Phospho-Tyk2 (Tyr1054 + Tyr1055) (TMAB-01526) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 134 kDa
Observed band size: 134 kDa
2. Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by microwave in sodium citrate buffer (pH6.0); Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (3% BSA) at RT for 30 min; Antibody incubation with (Phospho-Tyk2 (Tyr1054 + Tyr1055)) Polyclonal Antibody, Unconjugated (TMAB-01526) at 1:400 overnight at 4°C, followed by conjugation to the secondary antibody (labeled with HRP) and DAB staining.
3. Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by microwave in sodium citrate buffer (pH6.0); Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (3% BSA) at RT for 30 min; Antibody incubation with (Phospho-Tyk2 (Tyr1054 + Tyr1055)) Polyclonal Antibody, Unconjugated (TMAB-01526) at 1:400 overnight at 4°C, followed by conjugation to the secondary antibody (labeled with HRP) and DAB staining.
4. Paraformaldehyde-fixed, paraffin embedded (Human kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (Phospho-Tyk2 (Tyr1054 + Tyr1055)) Polyclonal Antibody, Unconjugated (TMAB-01526) at 1:200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining.
verifiedActivityverifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Tissue SpecificityObserved in all cell lines analyzed. Expressed in a variety of lymphoid and non-lymphoid cell lines.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundThis gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq].
Antigen Details
Immunogen
KLH conjugated Synthesised phosphopeptide: human Tyk2 around the phosphorylation site of Tyr1054/1055
Antigen Species
Human
Gene Name
TYK2
Gene ID
Protein Name
Non-receptor tyrosine-protein kinase TYK2
Uniprot ID
Biology Area
SARS Coronavirus,Tyrosine Kinases
Function
Probably involved in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Phosphorylates the interferon-alpha/beta receptor alpha chain.
Chemical Properties
Molecular WeightTheoretical: 134 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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